OBJECTIVES: To evaluate pharmacy clinical interventions done in the children cancer hospital Egypt during the period from July 2007 to March 2009. METHODS: The clinical intervention reports were recorded into a database made by the department of pharmaceutical services. RESULTS: A total of 362 Pharmacy Clinical interventions were recorded(this number constitute only 40% of the daily interventions), 52(14.4%) were category A, which is Incomplete prescription (missing: Generic name, drug form, strength, dose, duration…..etc.); 58(16%) were category B, which is Irrational prescribing; 39(10.8%) were category C, which is Excessive quantities, Unnecessary medication Duplication of therapy; 152 (41.99%) were category D, which is inappropriate dosage/route/flow rate/duration of therapy, where from the 152 Intervention in category D 65% was Inappropriate dosage, 15% inappropriate flow rate and 20% inappropriate duration of treatment; 25 (6.9%) were category E Drug-drug interactions; 8(2.2%) were category F, which is Allergy to a prescribed medicine; 11(3%) were category G, which is Drug incompatibilities-Disease e.g.  G6PDD-Food -Lab tests; 14(3.9%) were category H, which is Drug monitoring is needed; 1 Intervention was category I, which is Dose adjustment is needed due to renal insufficiency and 2 were category J which is Dose adjustment is needed due to hepatic insufficiency. CONCLUSIONS: The 362 Pharmacy clinical interventions were all medical errors that were prevented by the pharmacy staff. The major intervention was mainly category D regarding inappropriate dosage. The Pharmacy Clinical Intervention database will be used now on the floors, to encourage participation from the pharmacists and increased the reporting .