Valuation of SF-6D Health States: Is It Feasible and Acceptable in a Lebanese Population

Author(s)

Kharroubi S1, El Harakeh M2, Dawoud D3, Rowen D4, Brazier JE4
1American University of Beirut, Beirut, Lebanon, 2American University of beirut, Beirut, Lebanon, 3National Institute for Health and Care Excellence, London, UK, 4University of Sheffield, Sheffield, UK

OBJECTIVES

: The SF-6D is a preference-based measure of health derived from the SF-36 for economic evaluation. No value set exists for the SF-6D in Lebanon and other Arabic speaking countries in the Middle East. The aim of this study was to examine the feasibility and acceptability of using the standard gamble (SG) technique to generate preference‐based values for the Arabic version of SF‐6D in a Lebanese population.

METHODS

: The SF‐6D was translated into Arabic using forward and backward translations. Forty‐nine states defined by the SF‐6D were selected using an orthogonal design and grouped into seven sets. A gender‐occupation stratified sample of 126 Lebanese adults from the American University of Beirut were recruited to value seven states and the pits (worst) SF-6D health states using SG. Mean and individual level multivariate regression models were fitted to estimate preference weights for all SF‐6D states. The quality of data and the predictive power of the models were compared with results from the United Kingdom.

RESULTS

: A total of 992 (98% out of 1008 observations) SG valuations were useable for econometric modeling. There was no significant change in the test–retest values from 21 subjects. The mean absolute errors in the mean and individual level models were 0.036 and 0.050, respectively, both of which were lower than the UK results. The random effects model adequately predicts the SG values, with the worst state having a value of 0.322 compared to 0.271 in the UK.

CONCLUSIONS

: This study confirmed that it was feasible and acceptable to generate preference values with the SG method for the Arabic SF‐6D in a Lebanese population. Further research is needed to extend this to a more representative population. However, this work would be the first step towards developing SF-6D value set for Lebanon to be used in economic evaluation studies.

Conference/Value in Health Info

2022-05, ISPOR 2022, Washington, DC, USA

Value in Health, Volume 25, Issue 6, S1 (June 2022)

Code

PCR175

Topic

Economic Evaluation, Methodological & Statistical Research, Patient-Centered Research

Topic Subcategory

Cost-comparison, Effectiveness, Utility, Benefit Analysis, Health State Utilities, Patient-reported Outcomes & Quality of Life Outcomes

Disease

No Additional Disease & Conditions/Specialized Treatment Areas

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