Influencing Factors and Economic Burden of Carbapenem Resistant Klebsiella Pneumoniae Pulmonary Infection in Neurosurgical Patients
Author(s)
Su D1, Zhou R2
1The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 34, China, 2The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, China
OBJECTIVES : To explore and analyze the clinical characteristics and economic burden of carbapenem resistant klebsiella pneumoniae infection in neurosurgical patients of a third grade hospital, so as to develop effective programs for infection prevention and intervention and reduce the economic burden of patients. METHODS : Neurosurgical patients admitted to a third grade hospital for neurosurgery from January 2018 to October 2019 were selected as the research objects,and the basic information of pulmonary infection of klebsiella pneumoniae resistant to carbapenems and the hospitalization expenses and length of stay in the two groups were compared through the analysis of the matched neurosurgical patients. RESULTS : Patients with carbapenem resistant klebsiella pneumoniae infection in neurosurgery were mostly middle-aged and elderly males (mean age 58.83 ± 13.98, with males accounting for 68.30%). The Glasgow coma scale (7.07 ± 3.11 in the infected group and 9.46 ± 3.61 in the non-infected group, P = 0.002) was generally lower. Tracheotomy (infected group 39, non-infected group 8, P < 0.001) and mechanical ventilation (infected group 32, non-infected group 12, P < 0.001) increased the number of cases during the treatment. The total hospitalization expenses of patients in the infection group were RMB 136247.45 (79243.86,185037.09), RMB 47979.24 (20528.15, 73469.33) in the non-infection group, and RMB 88268.21(25679.52,130001.45) in the economic burden of carbapenem resistant klebsiella pneumoniae pulmonary infection. Carbapenem - resistant klebsiella pneumoniae pulmonary infection prolonged the hospital stay of neurosurgical patients by 22.37(3.50,34.00) days. CONCLUSIONS Patients with carbapenem resistant klebsiella pneumoniae infection in neurosurgery had lower Glasgow coma scale than non-infected patients, longer hospitalization days, and increased economic burden. Invasive operations such as tracheotomy and mechanical ventilation during treatment increased the risk of infection.
Conference/Value in Health Info
2021-05, ISPOR 2021, Montreal, Canada
Value in Health, Volume 24, Issue 5, S1 (May 2021)
Code
PIN71
Topic
Economic Evaluation, Epidemiology & Public Health, Health Service Delivery & Process of Care
Topic Subcategory
Hospital and Clinical Practices
Disease
Infectious Disease (non-vaccine), Injury and Trauma, Surgery