PURPOSE: This workshop introduces the sandbox approach and explains its possible applications in health technology assessment (HTA), using methodological and policy challenges around real world data (RWD) for HTA-decisions. Attendees should walk away with insight in why it would be beneficial and how it might work to engage all stakeholders in such a complex environment to test emerging methods, policies and processes.

DESCRIPTION: In 2022, a policy sandbox will be organized in the Horizon2020 funded project HTx (Next Generation Health Technology Assessment) to test new methods to make better use of RWD. There is a growing recognition of the value of RWD in addition to efficacy data from RCTs. However, some hurdles remain in benefiting from the use of RWD. A policy sandbox is a safe environment where the outcomes of the project can be translated into HTA practice while engaging stakeholders. We have seen that it is crucial for the acceptance and uptake of any new method that stakeholders are engaged during development. Despite its potential, this is the first time that a sandbox will be applied in HTA-setting.

Milou Hogervorst will give a background on the willingness to use RWD for HTA decisions in challenging circumstances (8 min.). Secondly, Johan Pontén will elaborate on the identified challenges of using RWD in HTA (10 min.). Thirdly, Ayla Lokhorst will outline useful change models for engaging stakeholders (10 min.). Finally, Dalia Dawoud will present the concept of policy sandboxes and its use as a controlled environment to test new HTA methods (13 min.). Q&A time will be given at the end and questions will be asked on other examples/situations where it would be useful to apply the policy sandbox format (19 min.). This workshop will be very relevant for attendees from various backgrounds including academics, HTA agencies and pharmaceutical companies.