QUALITY EVALUATION OF PHARMACOECONOMIC STUDIES IN RUSSIAN CANCER RESEARCH- AN OUTSIDE VIEW
Author(s)
Djalalov S1, Djalalova D2, Krahn M3, Matveev N4, Hoch J5
1Westminster International University in Tashkent, Tashkent, ON, Canada, 2Tashkent Pedagogical University, Tashkent, Uzbekistan, 3Toronto Health Economics and Technology Assessment (THETA) Collaborative, Toronto, ON, Canada, 4Pirogov Russian National Research Medical University, Moscow, Russian Federation, 5University of California Davis, Sacramento, CA, USA
OBJECTIVES : This study aimed to assess the scope and quality of economic evaluations in oncology, with the goal of elucidating implications for improving their use in Russia. METHODS : Online databases were searched for oncologic economic evaluations written in Russian. Data were extracted and assessed with the Quality of Health Economic Studies (QHES) instrument. In addition, the QHES was modified to overcome double–barreled items in a single criterion. RESULTS : Of 29 articles identified, 15 met study criteria and were included in the review. The majority of studies analyzed Cost-Effectiveness of 1st and 2nd line therapies for lung and kidney cancer. The others analyzed prostate, breast, colorectal cancers and lymphoma. The QHES mean quality score for the reviewed studies was 74 (and 69 with the modified tool). Comparison of the quality of different study types revealed that cost utility studies and studies that used decision trees and Markov models had the highest mean quality score. Clear statement regarding bias, study limitations, uncertainty, study perspectives and funding source were commonly absent in the reviewed studies. CONCLUSIONS : Our review indicates that oncologic economic evaluations published in Russian are limited in scope and number. In addition, they demonstrate opportunities for improvement in several important technical areas.
Conference/Value in Health Info
2019-05, ISPOR 2019, New Orleans, LA, USA
Value in Health, Volume 22, Issue S1 (2019 May)
Code
PCN252
Topic
Health Service Delivery & Process of Care, Methodological & Statistical Research, Organizational Practices
Topic Subcategory
Best Research Practices, Quality of Care Measurement, Survey Methods
Disease
Drugs, Oncology
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