THE IMPACT OF ANTIBIOTIC TREATMENT TIME AND CLASS OF ANTIBIOTIC FOR ACUTE OTITIS MEDIA INFECTIONS ON THE RISK OF REVISITS
Author(s)
Sangha K, Steinberg I, McCombs JS
University of Southern California, Los Angeles, CA, USA
BACKGROUND Acute otitis media (AOM) in children is commonly treated with antibiotics, yet limited data of prescribing patterns and the outcomes exists. OBJECTIVES : Document factors affecting antibiotic prescribing patterns for pediatric AOM patients and estimate the effects of antibiotic prescribing on the likelihood of revisits within 28 days. METHODS : Optum Insight Clinformatics claims data from 2011-2013 were used to identify children (<18 years old) diagnosed with AOM. An episode of care was defined around the first AOM visit (+/- 6 months). Multivariable logistic regression was used to identify demographic and clinical factors associated with antibiotic use. A similar model was used to estimate the effect of treatment on the likelihood of initiating a revisit within 28 days. RESULTS : 2378 (64%) of 3747 children with AOM were treated with an antimicrobial within 28 days, and only 57% of treated patients had their antibiotic prescription filled within 3 days. The likelihood of filling within 3 days increased with age and co-morbid fever or URI, and was lower among patients with a prior respiratory infection. Children receiving the antibiotic within 3 days had a reducedrisk of a revisit within 28 days (adjusted OR=0.439, p<0.001) than those who received the antibiotic in 4-28 days, or who were not treated. Children receiving an antibiotic on the index visit day had 62% lower risk of a revisit (p<0.001) within 28 days than the children who were not treated.Children < 1 year old were 2.4 times more likely to initiate a revisit. Class of antibiotic prescribed did not impact revisit risk. The statistical factors and magnitude were similar for revisits within 7 and 28 days. CONCLUSIONS : AOM patients filling an antibiotic prescription on or within 3 days of the index visit are less likely to initiate a return visit within 7 to 28 days.
Conference/Value in Health Info
2019-05, ISPOR 2019, New Orleans, LA, USA
Value in Health, Volume 22, Issue S1 (2019 May)
Code
PDG4
Topic
Clinical Outcomes, Real World Data & Information Systems
Topic Subcategory
Comparative Effectiveness or Efficacy, Health & Insurance Records Systems
Disease
Infectious Disease (non-vaccine)