Quality of Life of Rheumatoid Arthritis Patients Under Biological Therapy in Morocco and Associated Factors: Ecoram Study

Author(s)

Zarrik H1, Hassani AC2, Slaoui M3, Rkain H4, Allali F4, Bahiri R4, Ahid S5
1University Mohamed V, Rabat, Morocco, 2University Mohamed V, Rabat, morocco, Morocco, 3university Mohamed VLaboratory of Histology, Embryology and Cytogenetics,, Rabat, Morocco, 4El Ayachi Hospital, Rabat, Rabat, Morocco, 5Pharmacoeconomics & Pharmacoepidemiology Research Team Mohammed V University, Rabat, Rabat, Morocco

OBJECTIVES: To evaluate the quality of life of patients with Rheumatoid arthritis (RA) and the impact of the type of BDMARDs used after 6 and 12 months following therapy.

METHODS: We included 110 patients with RA admitted and followed-up at the rheumatology services of ELAYACHI Hospital. The QoL was assessed using EQ-5D-3L and EQ-VAS. Univariate analyses were applied to identify factors associated to EQ-5D scores.

RESULTS: Eighty-five percent of patients were female with a mean age of 50.53 ± 13.86 years and a mean disease duration of 10.14±7.03 years. The mean EQ-5D score was 0.32±0.30 in S1 versus 0.71± 0.33 in S2. In addition, the mean EQ-VAS score was 44.75± 16.72 in S1 versus 58.73±17.69 in S2 and the differences were statistically significant between S1 and S2 (p=0.000). The QOL of patients with RA was associated significantly with the kind of biological therapy used and to other parameters.

CONCLUSIONS: QOL of patients with RA is significantly higher after 6 and 12 months following therapy with BDMARDS and affected almost the five dimensions of the EQ-5D. Several factors were associated with EQ-5 D, EQ-VAS scores, including the type of biological medicines used, some sociodemographic and clinical parameters.

Conference/Value in Health Info

2024-11, ISPOR Europe 2024, Barcelona, Spain

Value in Health, Volume 27, Issue 12, S2 (December 2024)

Code

CO137

Topic

Clinical Outcomes, Economic Evaluation

Topic Subcategory

Clinical Outcomes Assessment, Performance-based Outcomes, Work & Home Productivity - Indirect Costs

Disease

No Additional Disease & Conditions/Specialized Treatment Areas, Systemic Disorders/Conditions (Anesthesia, Auto-Immune Disorders (n.e.c.), Hematological Disorders (non-oncologic), Pain)

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