Assessing Changes in the Number and Profile of New Cases of Bacterial Sexually Transmitted Infections From 2018-2021: A Descriptive Analysis of German Claims Data

Author(s)

Rios Chavarria RF1, Knapp R2, Hardtstock F2, Wilke T3, Maywald U4
1Cytel Inc., Berlin, BE, Germany, 2Cytel Inc., Berlin, Germany, 3IPAM e.V., Wismar, Germany, 4AOK PLUS, Dresden, Germany

Presentation Documents

OBJECTIVES: We compared the number and profile of patients diagnosed with bacterial sexually transmitted infections (STI) before and during the global pandemic.

METHODS: Our study used German claims data provided by AOK PLUS from 01/01/2017-30/06/2021. Continuously insured adults with one inpatient and/or outpatient diagnosis of chlamydia (ICD-10 A55/A56), gonorrhea (A54), or syphilis (A51/A53) were included. The number of new STI cases was assessed quarterly from 2018-2021. A window of 180 days was used to detect new infections, as re-infections are possible.

RESULTS: Overall, 10,222 individuals (11,685 cases) were included. Approximately 60.4% were female, with a mean/median age of 31.9/28.0 years. Only 3.1% received an STI code at baseline.

Chlamydia was the most common STI (77.2%), followed by gonorrhea (13.2%) and syphilis (9.6%). Females recorded more chlamydia (67.4%), while males accounted for a higher share of syphilis (76.9%) and gonorrhea (61.3%) cases. Chlamydia patients were younger at diagnosis (mean/median: 29.9/26.0 years) than gonorrhea (38.4/35.0) and syphilis (41.9/40.0) patients.

From 2018-2021, the number of new chlamydia and syphilis cases fluctuated. A decrease in new gonorrhea cases was observed beginning in Q2 2020 (median/range: 93/83-110 vs. 118/101-137 in the pre-COVID period). The share of women with gonorrhea diagnoses was disproportionately lower during COVID compared to pre-COVID (median/range: 33.7%/27.4-38.1% vs. 42.6%/37.1-47.1% during pre-COVID). While no difference in age profile was observed for gonorrhea or syphilis, the age of patients with chlamydia during COVID was slightly lower (29.2 vs. 31.0 during pre-COVID).

CONCLUSIONS: Fewer women received gonorrhea diagnoses during the COVID period, and the average age of chlamydia patients dropped. Further research is needed to assess whether these trends are suggestive of under-diagnosis or systematic changes in risk-taking behavior during lockdown.

Conference/Value in Health Info

2022-11, ISPOR Europe 2022, Vienna, Austria

Value in Health, Volume 25, Issue 12S (December 2022)

Code

EPH189

Topic

Epidemiology & Public Health

Topic Subcategory

Public Health

Disease

SDC: Infectious Disease (non-vaccine)

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