OBJECTIVES

: Stroke is the second most common cause of death after ischaemic heart disease in Hungary. The purpose of this study is the comparison of risk factors and health outcomes of patients with acute ischaemic stroke (AIS) receiving different treatments.

METHODS

: Analysis was conducted on data of patients treated at the University of Pécs Clinical Centre between 2017 and 2020. The selection criteria were patients with AIS, with onset-to-door time below 24 hours, pre-stroke functional independence (defined by a modified Ranking Score [mRS] of 0-2) and written consent form signed by the patient or an attendant. Our sample consists of 452 patients, of which 163 were nonrecanalised, 171 received intra-arterial thrombolysis (IVT), 75 mechanical thrombectomy (MT) and 43 both IVT and MT. Follow-up mRS scores were taken 30, 90, and 365 days after discharge from hospital. Descriptive statistical analysis was conducted exploring patient characteristics and health outcomes.

RESULTS

: Patients had a median age of 70 years (IQR: 17.00) and 54.65% were males. The median onset-to-door time in hours was 7.18 (IQR: 9.91) for nonrecanalised, 1.29 (IQR: 1.19) for IVT, 3.58 (IQR: 5.86) for MT and 1.31 (IQR: 0.93) for IVT+MT patients. The median National Institutes of Health Stroke Scale (NIHSS) score at discharge was 4.00 (IQR: 5.00) for nonrecanalised, 1.00 (IQR: 3.00) for IVT, 6.00 (IQR: 11.00) for MT and 7 (IQR: 9.00) for IVT+MT patients. The median mRS score one year after discharge was 2.00 (IQR: 6.00) for nonrecanalised, 0.00 (IQR: 3) for IVT, 3.00 (IQR: 5.00) for MT, and 2.00 (IQR: 5.00) for IVT+MT patients.

CONCLUSIONS

: Descriptive analysis shows differences in health outcomes between patients with different treatments. The highest rate of worst outcomes were observed for MT patients and the lowest for IVT patients. Further analysis controlling for patient characteristics is required to further explore these differences.