OBJECTIVES

Cutaneous T-cell lymphoma (CTCL) is a rare but prevalent disorder that have significant impact on patient’s quality of life (QOL). A considerably high proportion of patients with CTCL experience psychosocial burden and mental-health problems. The objective of the study was to review and understand the psychological impact of the CTCL on patient’s daily life.

METHODS

A systematic literature searches were performed using Medline and EMBASE to identify studies that measured the psychological impact of CTCL. The search strategy was based on combination of key words included for ‘CTCL’, HRQoL, psychological stress etc.

RESULTS

In total, seven studies were identified that discussed the psychological impact of CTCL. Clinical symptoms such as skin fissures, sores and skin flaking have a significant impact on patients’ psychological and social well-being, particularly in relation with self-image and concerns about appearance. Four studies highlighted that females are more impacted as compared to men. Majorly, the patients experience depression due to uncertainty associated with the disease as they are unaware of the disease course and prognosis. As the severity of the disease increases, futility and uncertainty related to disease is higher. Delay in diagnosis or misinterpretation of the disease can further impact the patients’ mental health. Due to social stigmatization and lack of awareness about the disease in society, acceptance necessary for patient’s well-being is not available due to which patient’s tend to self-isolate.

CONCLUSIONS

CTCL indirectly impacts patient and society’s perception. This often results in social stigmatization and physical and social isolation of patient which effects patient’s psychology unfavorably. Considering the psychological burden, it is highly recommended to raise awareness of CTCL within the community by encouraging local media coverage and provide mindfulness therapies to the patients to cope with disease in long-term.