OBJECTIVES: Multiple myeloma (MM) – uncontrolled division of malignant plasma cells in bone marrow tissue – is the second most prevalent hematological malignancy in the world. The complexity of the treatment regimens requires continuous effort and attention from patients, when taking (oral) medication. This in particular given the higher ages, higher levels of frailty and disability of MM patients if compared with other types of cancer patients. Therefore, this study aims to investigate the feasibility of applying a newly developed MM e-coach with an integrated medication module and user experience from patients and healthcare professionals, for further development.

METHODS: This study was designed as a single centre trial that aimed to include 20 patients. At the start and week 8, all patients received a system usability scale (SUS) form. Also, monitoring of patient reported outcomes (PRO) was done based on measurements at time of inclusion as well as week 8. E-coach experiences of health care professionals (n=5) were measured and summarized with the following items: ease of use, user satisfaction, functionality, time efficiency, patient feedback, diversity and technical complaints.

RESULTS: Based on applying dynamic implementation of the MM e-coach, SUS results improved and specific outcomes for communication, medication intake and side effect management, resulted in lower treatment related adverse events. Furthermore, we identified potential for improvement in the quality of MM care by sufficient patient preparation and implementation of a (digital) consult as part of a multi-component intervention strategy.

CONCLUSIONS: This feasibility study reveals proof of promise in terms of treatment optimization, PROs and the positive experience of health care professionals. Further implementation evaluation will follow additional extensive MM e-coach implementation process monitoring.