METABOLICS SYNDROME AND COMPLICATIONS PREGNANT WITH PCOS
Author(s)
Komlósi K1, Kiss S1, Ferenczy M1, Oláh A2, Szabó L2, Póhr K1, Boncz I2, Pakai A3
1University of Pécs, Szombathely, Hungary, 2University of Pécs, Pécs, Hungary, 3University of Pécs, Pécs, ZA, Hungary
OBJECTIVES : In our research we compared whether pregnant women with polycystic ovary syndrome or the mothers who were healthy through pregnancy has a higher risk to develop high BMI, metabolic syndrome, preeclampsia, polyhydramnion and macrosomia. METHODS : Our research is a retrospective, cross-sectional study. In the random sampling within the target group, the target group was diagnosed with PCOS (n=50) and the control group was mothers who had undergone uninterrupted pregnancy (n=50). The exclusion criterion is the coexistence of other endocrine disease that may affect the parameters under consideration, in addition to the control group the diagnosis of PCOS. During our research, we worked with 11 years of patience population, we examined a total of 100 test data and patient records through document analysis at the Medsol system of the Markusovszky University Hospital. The data collection was carried out between 1 January 2017 and 31 December 2017.With IBM SPSS for Windows 22.0, we applied two-sample T-test and Khi2test (p<0.05). RESULTS : The BMI values measured in the PCOS study group are higher than in the control group (p<0.001). Pregnant women with PCOS has a higher risk of developing high blood pressure (p=0.037), high cholesterol (p<0.001) and triglyceride levels (p=0.014) but not gestational diabetes mellitus (p=0.121). The difference between the two groups can not be considered significant for the development of proteinuria (p=0.193) and oedema (p=0.526). A higher proportion of polyhydramnion (p=0.0123) is found in PCOS pregnancies, but macrosomy (p=0.110) does not occur more frequently in this group. CONCLUSIONS : In view of the results obtained, the presence of PCOS diagnosis affects BMI values, blood pressure, cholesterol and triglyceride levels, and polyhydramnion occurs more frequently. It does not affect the prevalence of GDM, preeclampsia and macrosomia.
Conference/Value in Health Info
2019-11, ISPOR Europe 2019, Copenhagen, Denmark
Code
PIH6
Topic
Clinical Outcomes
Topic Subcategory
Clinical Outcomes Assessment
Disease
Diabetes/Endocrine/Metabolic Disorders, Reproductive and Sexual Health