Incidence, Mortality, Hospitalizations, and Expenditures for Pemphigus in Taiwan

Author(s)

Chang CJ1, Chiu HY2, YuJr L3, Tsai TF4
1National Evidence-Based Healthcare Collaborating Agency, Seoul, Korea, Republic of (South), 2National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan, 3Chang Gung University, Taipei, Taiwan, 4National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan

OBJECTIVES

:
To describe national trends in incidence, mortality, hospitalizations, and expenditures in pemphigus between 2003 and 2015.

METHODS

:
This nationwide study used the Registry of Catastrophic Illness Patients of Taiwan National Health Insurance Research Database to identify patients with pemphigus from 2003 to 2015. Annual incidence, prevalence, health care utilization and expenditure were calculated, and time-trend analyses were estimated.

RESULTS

:
The incidence of pemphigus increased significantly from 3.19 in 2003 to 4.70 per million person years in 2010, but fluctuated from 2011 to 2015. Compared with non-pemphigus subjects, individuals with pemphigus had a higher mortality rate and cost of care. From 2003 to 2015, the medical utilization and expenditure for hospital inpatient and outpatient in patients with pemphigus decline accompanied by decreasing systemic corticosteroids use, whereas the mortality rate remained stable.

CONCLUSIONS

:
Over a recent 12 years, reduction in health expense for pemphigus was mainly attribute to a decrement in utilization, length of stay and costs related to hospital inpatients. The persistently elevated mortality rate highlighted a still unmet need in pemphigus therapy.

Conference/Value in Health Info

2020-09, ISPOR Asia Pacific 2020, Seoul, South Korea

Value in Health Regional, Volume 22S (September 2020)

Code

PRO18

Topic

Clinical Outcomes, Epidemiology & Public Health, Real World Data & Information Systems

Topic Subcategory

Clinical Outcomes Assessment, Health & Insurance Records Systems

Disease

Rare and Orphan Diseases

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