OBJECTIVES

:

• To assess QOL in patients with metastatic breast canc er and its pharmaceutical management, To assess the QOL in patients with metastatic breast cancer,To emphasize the pharmaceutical care in improving QOL.
• METHODS:The data was collected in the designed data collection form. After the necessary data was collected Assessment of quality of life was performed by using self-designed and validated questionnaire (which was taken from European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Breast Cancer {EORTC QLQ-BR23} and Functional Assessment of Cancer Therapy-Breast Cancer {FACT-B}) was used to assess the quality of life in metastatic breast cancer patients which consists of 30 closed ended questions .

RESULTS:Based on the results obtained our study revealed that 16 (30.76%) of the 52 subjects the first distant metastasis was to bone. Of the 18 subjects whose first metastasis was to the viscera, the organ most often involved was the liver (n=9 ; 17.30%) followed by lung (n=6 ; 11.53%) and brain (n=3 ;5.77%) .These findings were in concordance with study done by Linda Vona-Davis et al., (2014) conducted a study on “Breast Cancer Pathology, Receptor Status, and Patterns of Metastasis in a Rural Appalachian Population[6]” and 9 out of 52 subjects were diagnosed with recurrence(17.30%) . remaining 9 subjects were diagnosed with multiple site metastasis i.e., out of 9 (17.30%) 3 subjects were diagnosed with lung ,bone (5.77%) and bone, recurrence(n=1 ;1.92%),liver , recurrence (n=1 ; 1.92%) , liver ,brain (n=1 ;1.92 %),liver , lung (n=1 ; 1.92%) bone, liver (n=1 ;,1.92%) lung , bone ,liver (n=1 ; 1.92%).

CONCLUSIONS:Our study concludes that Pharmaceutical care and Psychosocial support and the provided patient information leaflet which was mainly focused on healthy diet plays a vital role in improving adherence to the therapy there by enhancing the QOL of patients with metastatic breast cancer being treated with Bisphosphonates or chemotherapy and hormonal therapy.