OBJECTIVES: In Flanders, population screening programs for breast, cervical, and colorectal cancer are well-established. Lung cancer screening has not yet been implemented, despite its potential to significantly reduce lung cancer mortality through low dose computed tomography (LDCT) screening. Policymakers are evaluating whether a comprehensive lung cancer screening program could be introduced soon. To ensure successful implementation, it is crucial to understand the preferences and concerns of eligible participants. This study will identify key factors influencing screening participants' engagement, enabling healthcare professionals (HCPs) to address critical issues and enhance the screening program's overall effectiveness.

METHODS: An umbrella review and semi-structured interviews with eligible lung cancer screening participants (n=15) and HCPs (n=15) in Flanders will be held. Interviews will be transcribed ad verbatim and analyzed using thematic framework analysis. The themes identified from both the umbrella review and interviews will be categorized according to the CFR 2.0 framework [1]. The results will be narratively synthesized.

RESULTS: Preliminary findings from the umbrella review highlight key barriers to lung cancer screening. These include widespread concerns such as fear of diagnosis, concerns about radiation exposure, the financial burden associated with screening procedures, and logistical challenges such as transportation issues. Further insights and detailed results from the ongoing literature and planned interview study will be presented during the ISPOR 2024 congress.

CONCLUSIONS: To establish an effective lung cancer screening program in Flanders, addressing barriers such as fear of diagnosis, radiation exposure concerns, financial limitations, and logistical challenges is crucial. Considering these preferences and concerns can enhance the development of a more effective screening program in Flanders. In a next step, this approach facilitates tailoring screening recommendations to each person's individual needs during shared decision-making counseling visits.