UTILITY WEIGHTS IN CHRONIC DISEASE IN LEBANON: A GENERAL POPULATION BASED STUDY
Author(s)
Fatima Dayeh, BA1, Caline Saade, PharmD2, Samer Kharroubi, PhD1, Fatima Al Sayah, PhD2.
1American University of Beirut, Beirut, Lebanon, 2Center of Clinical, Health Economics and Outcomes Research, Dubai, United Arab Emirates.
1American University of Beirut, Beirut, Lebanon, 2Center of Clinical, Health Economics and Outcomes Research, Dubai, United Arab Emirates.
OBJECTIVES: To estimate EQ-5D-5L utility decrements associated with major chronic diseases in the Lebanese adult population and quantify their impact on self-reported health status.
METHODS: A cross-sectional online survey was conducted among 519 adults in Lebanon between March and September 2024. Quota sampling based on age, sex, and geographic region was used to obtain a representative sample. Participants completed sociodemographic questionnaires, EQ-5D-5L, SF-12v1, and Beirut Distress Scale (BDS). EQ-5D-5L utility scores were calculated using the Egypt value set as no value set is available for Lebanon. Utility decrements associated with self-reported chronic diseases were estimated by comparing mean EQ-5D-5L utility scores and EQ visual analogue scale (EQ VAS) scores between respondents with and without each condition.
RESULTS: Mean (SD) age of participants was 38.2 (16.5) years, and 55.5% were female. Most respondents reported no problems with mobility (77.3%), self-care (91.4%), and usual activities (74.1%); however, problems with pain/discomfort (55.2%) and anxiety/depression (43.1%) were common. 27.8% reported one chronic condition, and 29.9% reported two or more chronic conditions. The EQ-5D-5L demonstrated a ceiling effect of 21.8% (11111) and a floor effect of 0.2% (55555). Mean (SD) EQ-5D-5L utility and EQ VAS scores were 0.798 (0.276) and 74.2 (19.0), respectively. Musculoskeletal disease was associated with the greatest utility decrement (-0.405), corresponding to a mean utility score of 0.393 (SD 0.472), followed by cardiovascular disease (-0.201), bowel disease (-0.197), mental health disorders (-0.165), migraine (-0.114), and obesity (-0.098). Similar patterns were observed for EQ VAS scores, with the largest reductions reported among respondents with musculoskeletal disease (-19.7 points) and cardiovascular disease (-15.2 points).
CONCLUSIONS: Chronic diseases are associated with substantial reductions in health-related quality of life among adults in Lebanon, with musculoskeletal and cardiovascular conditions exerting the greatest burden. These disease-specific utility estimates provide locally relevant inputs that can support healthcare priority setting and decision-making in Lebanon.
METHODS: A cross-sectional online survey was conducted among 519 adults in Lebanon between March and September 2024. Quota sampling based on age, sex, and geographic region was used to obtain a representative sample. Participants completed sociodemographic questionnaires, EQ-5D-5L, SF-12v1, and Beirut Distress Scale (BDS). EQ-5D-5L utility scores were calculated using the Egypt value set as no value set is available for Lebanon. Utility decrements associated with self-reported chronic diseases were estimated by comparing mean EQ-5D-5L utility scores and EQ visual analogue scale (EQ VAS) scores between respondents with and without each condition.
RESULTS: Mean (SD) age of participants was 38.2 (16.5) years, and 55.5% were female. Most respondents reported no problems with mobility (77.3%), self-care (91.4%), and usual activities (74.1%); however, problems with pain/discomfort (55.2%) and anxiety/depression (43.1%) were common. 27.8% reported one chronic condition, and 29.9% reported two or more chronic conditions. The EQ-5D-5L demonstrated a ceiling effect of 21.8% (11111) and a floor effect of 0.2% (55555). Mean (SD) EQ-5D-5L utility and EQ VAS scores were 0.798 (0.276) and 74.2 (19.0), respectively. Musculoskeletal disease was associated with the greatest utility decrement (-0.405), corresponding to a mean utility score of 0.393 (SD 0.472), followed by cardiovascular disease (-0.201), bowel disease (-0.197), mental health disorders (-0.165), migraine (-0.114), and obesity (-0.098). Similar patterns were observed for EQ VAS scores, with the largest reductions reported among respondents with musculoskeletal disease (-19.7 points) and cardiovascular disease (-15.2 points).
CONCLUSIONS: Chronic diseases are associated with substantial reductions in health-related quality of life among adults in Lebanon, with musculoskeletal and cardiovascular conditions exerting the greatest burden. These disease-specific utility estimates provide locally relevant inputs that can support healthcare priority setting and decision-making in Lebanon.
Conference/Value in Health Info
2026-11, ISPOR Europe 2026, Vienna, Austria
Value in Health, Volume 29, Issue 12S
Code
PCR174
Topic
Epidemiology & Public Health, Methodological & Statistical Research, Patient-Centered Research
Topic Subcategory
Health State Utilities, Patient-reported Outcomes & Quality of Life Outcomes
Disease
Cardiovascular Disorders (including MI, Stroke, Circulatory), Mental Health (including addiction), Musculoskeletal Disorders (Arthritis, Bone Disorders, Osteoporosis, Other Musculoskeletal), Neurological Disorders, Urinary/Kidney Disorders