GLOBAL LANDSCAPE OF FISCAL HEALTH MODELING FOR IMMUNIZATION: A TARGETED LITERATURE REVIEW

Author(s)

Laigle Valérie, PharmD1, Alain Dutilleul, MSc2, Mikaela Dock, PharmD2, Sreenu Lavudiya, MPharm3, Antonio Robles, PhD1.
1Global Health Economics & Value Assesment, Sanofi Vaccines, Lyon, France, 2Global Vaccines Public Affairs, Sanofi Vaccines, Lyon, France, 3Global Health Economics & Value Assesment, Sanofi Vaccines, Hyderabad, India.
OBJECTIVES: Immunisation programmes are widely recognised as one of the most cost-effective public health interventions. However, they often compete with other national priorities amid government budget constraints. Fiscal Health Modelling (FHM) quantifies government fiscal returns from immunisation programmes by capturing tax revenue gains, productivity preservation, and reduced government transfers beyond healthcare costs. While evidence on FHM is growing globally, the full landscape of this evidence base across countries, disease areas, and methodological approaches remains unmapped. This targeted literature review aims to systematically identify and characterise the global evidence on FHM for immunisation programmes.
METHODS: A targeted literature review (TLR) was conducted to identify and synthesise evidence informing FHM without time or geographical limits. A structured search strategy was undertaken in Embase, using controlled vocabulary and free text terms related to immunisation programmes. Complementary grey literature searches were conducted in Google Scholar. Study selection followed a two-stage process comprising title and abstract screening and subsequent full-text review by two independent reviewers.
RESULTS: A total of 38 unique studies published between 2010 and 2026 were identified across 26 countries. Geographic representation was diverse, including studies from Europe, North America, Asia, Africa, and Latin America. Disease coverage included general vaccination frameworks (8), HPV (6), rotavirus (6), COVID-19 (5), influenza (4), paediatric immunisation programmes (4), multi-vaccine programmes (1), and methodological reviews (3). Publication activity increased markedly since 2020, with 22 of 38 studies (58%) published between 2020-2026. Studies employed diverse methodological approaches, with fiscal benefit-cost ratios, net tax revenue gains, averted healthcare costs, and transfer reductions as common outcome measures.
CONCLUSIONS: FHM evidence is geographically diverse and growing, across multiple immunisation programmes and countries. This expanding evidence base demonstrates FHM's potential to inform governmental resource allocation decisions across diverse settings, supporting sustained strategic public investment in immunisation programmes globally.

Conference/Value in Health Info

2026-11, ISPOR Europe 2026, Vienna, Austria

Value in Health, Volume 29, Issue 12S

Code

EPH205

Topic

Economic Evaluation, Epidemiology & Public Health

Topic Subcategory

Public Health

Disease

Vaccines

Your browser is out-of-date

ISPOR recommends that you update your browser for more security, speed and the best experience on ispor.org. Update my browser now

×