CHARACTERIZING PARTICIPANTS IN THE ONTARIO HIV TREATMENT NETWORK COHORT STUDY (OCS): A COMPARISON AMONG 14 SITES
Author(s)
Adrienne Chan, MD1, Soo Jin Seung, BSc2, Anisia Wong, MSc1, Shahryar Murshed, MSc1, Preeti Sharma, BSc1, Tsegaye Bekele, MSc3, Mustafa Karacam, PhD3, Lawrence Mbuagbaw, MD4.
1Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 2Manager, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 3Ontario HIV Treatment Network, Toronto, ON, Canada, 4McMaster University, Hamilton, ON, Canada.
1Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 2Manager, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 3Ontario HIV Treatment Network, Toronto, ON, Canada, 4McMaster University, Hamilton, ON, Canada.
OBJECTIVES: The Ontario HIV Treatment Network (OHTN) Cohort Study (OCS) is longitudinal research of people living with HIV and receiving care at one of the fourteen participating sites in Ontario, Canada. Started in 1996, it is one of the largest cohort studies in North America with over 8,000 participants. This study compares demographic, socioeconomic, and clinical characteristics of participants of the Sunnybrook Health Sciences Centre (SHSC) site in Toronto to the participants of other 13 sites (others).
METHODS: A total of 3,451 OCS participants who completed the annual OCS questionnaire (2022-2024) were included. Descriptive analyses compared SHSC participants to the others. Questions included age, sex, gender, sexual orientation, education, employment, antiretroviral therapy (ART) use, HIV viral load, comorbidities, and travel time.
RESULTS: Of the 3,451 participants, 534 were from SHSC and 2,917 from other sites. More SHSC participants were aged ≥70 years compared with others (12.9% vs. 8.1%), identified as heterosexual (43.6% vs. 34.5%), completed university education (37.3% vs. 32.8%), and were employed (53.4% vs. 46.5%). ART uptake was high across all sites (>97%), with lower public drug coverage for SHSC participants (41.6% vs. 49.8%). Fewer SHSC participants reported a recent HIV viral load <40 copies/mL compared with others (79.2% vs. 85.2%). Mental health conditions, high cholesterol, and hypertension were the most reported comorbidities across all sites. More SHSC participants reported traveling more than 1 hour to see their HIV care provider (26.8% vs. 11.9%). SHSC participants reported excellent or very good health at a higher frequency (53.2% vs. 43.6%).
CONCLUSIONS: SHSC participants have distinct demographic and socioeconomic characteristics, highlighting potential differences in aging, social determinants of health, and clinical outcomes. Understanding site-specific characteristics may help inform care delivery, resource allocation, and health outcomes. Additional questions regarding challenges accessing HIV care, and impact to productivity are being analyzed.
METHODS: A total of 3,451 OCS participants who completed the annual OCS questionnaire (2022-2024) were included. Descriptive analyses compared SHSC participants to the others. Questions included age, sex, gender, sexual orientation, education, employment, antiretroviral therapy (ART) use, HIV viral load, comorbidities, and travel time.
RESULTS: Of the 3,451 participants, 534 were from SHSC and 2,917 from other sites. More SHSC participants were aged ≥70 years compared with others (12.9% vs. 8.1%), identified as heterosexual (43.6% vs. 34.5%), completed university education (37.3% vs. 32.8%), and were employed (53.4% vs. 46.5%). ART uptake was high across all sites (>97%), with lower public drug coverage for SHSC participants (41.6% vs. 49.8%). Fewer SHSC participants reported a recent HIV viral load <40 copies/mL compared with others (79.2% vs. 85.2%). Mental health conditions, high cholesterol, and hypertension were the most reported comorbidities across all sites. More SHSC participants reported traveling more than 1 hour to see their HIV care provider (26.8% vs. 11.9%). SHSC participants reported excellent or very good health at a higher frequency (53.2% vs. 43.6%).
CONCLUSIONS: SHSC participants have distinct demographic and socioeconomic characteristics, highlighting potential differences in aging, social determinants of health, and clinical outcomes. Understanding site-specific characteristics may help inform care delivery, resource allocation, and health outcomes. Additional questions regarding challenges accessing HIV care, and impact to productivity are being analyzed.
Conference/Value in Health Info
2026-11, ISPOR Europe 2026, Vienna, Austria
Value in Health, Volume 29, Issue 12S
Code
PCR116
Topic
Clinical Outcomes, Patient-Centered Research, Real World Data & Information Systems
Topic Subcategory
Patient Behavior and Incentives, Patient-reported Outcomes & Quality of Life Outcomes
Disease
Infectious Disease (non-vaccine), No Additional Disease & Conditions/Specialized Treatment Areas