OBTAINING KEY ESTIMATES OF RESOURCE USE ASSOCIATED WITH HIDRADENITIS SUPPURATIVA MANAGEMENT: RESULTS FROM A UK-BASED ONLINE DELPHI STUDY
Author(s)
Waqas Ahmed, MSc1, Claire Edwards, BSc Hons2, Lynda Doyle, MSc2, Adam Gibson, PhD1, Jaclyn (Huei Ling) Loh, MSc, PharmD3, Louise Longworth, BSc, MSc, PhD4.
1Arrow Health Economics, Canterbury, United Kingdom, 2Incyte, Leatherhead, United Kingdom, 3Incyte BioSciences, London, United Kingdom, 4Arrow Health Economics, London, United Kingdom.
1Arrow Health Economics, Canterbury, United Kingdom, 2Incyte, Leatherhead, United Kingdom, 3Incyte BioSciences, London, United Kingdom, 4Arrow Health Economics, London, United Kingdom.
OBJECTIVES: Hidradenitis suppurativa (HS) is a chronic follicular occlusive skin condition affecting 0.77% of people in the United Kingdom. HS affects patient quality of life and healthcare systems because disease management requires multiple interventions. Existing healthcare resource utilization (RU) estimates may not reflect contemporary UK clinical practice. This study aimed to elicit annual estimates of healthcare RU for management of moderate and severe HS.
METHODS: A three-round Delphi survey was developed and administered online to a panel of 24 UK-based healthcare professionals (HCPs) who treat moderate to severe HS. 76 questions explored type, frequency, and other factors in the surgical and non-surgical management of HS involving RU across five HS Clinical Response (HiSCR) categories. Consensus thresholds were predefined, and responses were iteratively refined across rounds.
RESULTS: Consensus was achieved by 24 HCPs on 75 of 76 RU estimates (98.7%). When aggregated across different surgery types, the observed trends showed that rates of surgeries conducted in inpatient, emergency, and outpatient settings increased as HiSCR worsened. Additionally, the mean number of wound care visits increased as HiSCR worsened. Clear relationships between HiSCR and RU were not evident for specific surgery types, likely reflecting the heterogeneity of HS and varied approaches to disease management. The exception was incision and drainage; the annual proportion of patients undergoing these procedures increased from a mean (SD) of 6% (7.8%) for full responders to 31% (15.1%) for non-responders. For non-surgical management, the typical number of annual emergency visits, inpatient stays, and outpatient stays were highest for partial responders and non-responders. Respondents highlighted the multidisciplinary care burden associated with HS management, including wound care, mental health support, and community-based services.
CONCLUSIONS: Responses demonstrated that poor control of HS incurs significant surgical and non-surgical RU. These results form a robust data source for economic evaluations of HS treatments.
METHODS: A three-round Delphi survey was developed and administered online to a panel of 24 UK-based healthcare professionals (HCPs) who treat moderate to severe HS. 76 questions explored type, frequency, and other factors in the surgical and non-surgical management of HS involving RU across five HS Clinical Response (HiSCR) categories. Consensus thresholds were predefined, and responses were iteratively refined across rounds.
RESULTS: Consensus was achieved by 24 HCPs on 75 of 76 RU estimates (98.7%). When aggregated across different surgery types, the observed trends showed that rates of surgeries conducted in inpatient, emergency, and outpatient settings increased as HiSCR worsened. Additionally, the mean number of wound care visits increased as HiSCR worsened. Clear relationships between HiSCR and RU were not evident for specific surgery types, likely reflecting the heterogeneity of HS and varied approaches to disease management. The exception was incision and drainage; the annual proportion of patients undergoing these procedures increased from a mean (SD) of 6% (7.8%) for full responders to 31% (15.1%) for non-responders. For non-surgical management, the typical number of annual emergency visits, inpatient stays, and outpatient stays were highest for partial responders and non-responders. Respondents highlighted the multidisciplinary care burden associated with HS management, including wound care, mental health support, and community-based services.
CONCLUSIONS: Responses demonstrated that poor control of HS incurs significant surgical and non-surgical RU. These results form a robust data source for economic evaluations of HS treatments.
Conference/Value in Health Info
2026-11, ISPOR Europe 2026, Vienna, Austria
Value in Health, Volume 29, Issue 12S
Code
HTA119
Topic
Economic Evaluation, Health Technology Assessment
Disease
No Additional Disease & Conditions/Specialized Treatment Areas, Systemic Disorders/Conditions (Anesthesia, Auto-Immune Disorders (n.e.c.), Hematological Disorders (non-oncologic), Pain)