COST-CONSEQUENCE AND BUDGET IMPACT OF PATIENT BLOOD MANAGEMENT IN TWO CHINESE HOSPITALS
Author(s)
Pingping Lin, PhD1, Zhi Li, PhD2, Mehtap Tatar, PhD3, Wentao Sun, MSc4, Antonio Ramirez de Arellano Serna, MSc, DPhil5, Hongwen Ji, PhD1.
1Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences, Shenzhen, China, 2Yantai Yuhuangding Hospital, Qingdao University, Yantai, China, 3Director, Polar Health Economics and Policy Consultancy, Ankara, Turkey, 4CSL Vifor, Beijing, China, 5CSL Vifor, Glattbrugg, Switzerland.
1Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences, Shenzhen, China, 2Yantai Yuhuangding Hospital, Qingdao University, Yantai, China, 3Director, Polar Health Economics and Policy Consultancy, Ankara, Turkey, 4CSL Vifor, Beijing, China, 5CSL Vifor, Glattbrugg, Switzerland.
OBJECTIVES: Anaemia and allogeneic transfusion are risk factors for perioperative morbidity and mortality. Patient Blood Management (PBM) is an evidence-based, patient-centered approach that improves outcomes by managing and preserving the patient's own blood. This study evaluates the cost-consequence and budget impact of implementing the first pillar alone and all three pillars of PBM in two Chinese hospitals.
METHODS: Two cost-consequence and budget impact models were employed from a hospital perspective. Surgical volumes and unit costs were obtained from Fuwai Shenzhen Hospital (1,074 cardiovascular surgeries) and Yantai Yuhuangding Hospital (1,443 cardiovascular surgeries) in 2025, whereas clinical effect estimates for complication rate reductions were derived from published meta-analyses. Two scenarios were simulated in each hospital: Pillar 1 of PBM alone (preoperative anaemia management) and all three pillars of PBM. The models estimated the prevention of severe postoperative complications associated with anaemia and red blood cell transfusion.
RESULTS: PBM was the dominant strategy—lower costs, higher efficacy—in all four scenarios. Full PBM implementation would have prevented 27 severe complications at Fuwai Shenzhen Hospital and 40 at Yantai Yuhuangding Hospital, equivalent to averting one major adverse event (sepsis, renal failure, myocardial infarction or stroke) for every 36-40 cardiac procedures. Pillar 1 alone would have prevented 12 and 18 complications, respectively. The budget impact analysis showed that Pillar 1 alone delivered net savings of CNY 1.77 million at Fuwai Shenzhen Hospital and CNY 2.45 million at Yantai Yuhuangding Hospital, with full PBM generating additional net savings of CNY 0.96 million and CNY 1.38 million, respectively. By reducing perioperative RBC transfusion, full PBM also has meaningful implications for conserving blood resources. Sensitivity analyses confirmed the robustness of these findings.
CONCLUSIONS: In Chinese cardiac surgery practice, implementing either Pillar 1 alone or all three pillars of PBM may deliver substantial clinical benefits and cost savings at a manageable investment.
METHODS: Two cost-consequence and budget impact models were employed from a hospital perspective. Surgical volumes and unit costs were obtained from Fuwai Shenzhen Hospital (1,074 cardiovascular surgeries) and Yantai Yuhuangding Hospital (1,443 cardiovascular surgeries) in 2025, whereas clinical effect estimates for complication rate reductions were derived from published meta-analyses. Two scenarios were simulated in each hospital: Pillar 1 of PBM alone (preoperative anaemia management) and all three pillars of PBM. The models estimated the prevention of severe postoperative complications associated with anaemia and red blood cell transfusion.
RESULTS: PBM was the dominant strategy—lower costs, higher efficacy—in all four scenarios. Full PBM implementation would have prevented 27 severe complications at Fuwai Shenzhen Hospital and 40 at Yantai Yuhuangding Hospital, equivalent to averting one major adverse event (sepsis, renal failure, myocardial infarction or stroke) for every 36-40 cardiac procedures. Pillar 1 alone would have prevented 12 and 18 complications, respectively. The budget impact analysis showed that Pillar 1 alone delivered net savings of CNY 1.77 million at Fuwai Shenzhen Hospital and CNY 2.45 million at Yantai Yuhuangding Hospital, with full PBM generating additional net savings of CNY 0.96 million and CNY 1.38 million, respectively. By reducing perioperative RBC transfusion, full PBM also has meaningful implications for conserving blood resources. Sensitivity analyses confirmed the robustness of these findings.
CONCLUSIONS: In Chinese cardiac surgery practice, implementing either Pillar 1 alone or all three pillars of PBM may deliver substantial clinical benefits and cost savings at a manageable investment.
Conference/Value in Health Info
2026-11, ISPOR Europe 2026, Vienna, Austria
Value in Health, Volume 29, Issue 12S
Code
CO95
Topic
Clinical Outcomes
Topic Subcategory
Comparative Effectiveness or Efficacy
Disease
No Additional Disease & Conditions/Specialized Treatment Areas