CLINICAL AND ECONOMIC IMPACT ASSESSMENT OF HORMONAL IUD USE IN REDUCING UNPLANNED PREGNANCIES IN BRAZIL: REAL-WORLD ANALYSIS FROM A BRAZILIAN HEALTH INSURANCE COMPANY

Author(s)

JOSE MARIO ALVES JUNIOR, PhD, Ana Carolina Furian da Silva, MS, Nathalia Maria Mascarenhas Munhoes, MD, Indyanara Inacio Barreto, MSc, Fatima Filomena Mafra Christoforo, PhD, Aline de Oliveira Podadera, MD, Jose Emilio Duran Bueno, MD.
UNIMED CAMPINAS, CAMPINAS, Brazil.
OBJECTIVES: To quantify trends in the utilization of levonorgestrel-releasing intrauterine devices (L-IUD) and estimate the costs potentially avoided through the reduction of unplanned pregnancies (UP) in an insured population.
METHODS: Retrospective cohort study including beneficiaries aged 18-34 years, followed between 2020 and October 2025. The cohort included prior users and new insertions of 52 mg and 19.5 mg L-IUDs. Low-risk pregnancies composed the second cohort for cost analysis. All data were obtained from administrative records of a large Brazilian Health Insurance Company (Unimed Campinas). Prenatal and delivery costs were calculated using reimbursed amounts, and savings scenarios were modeled based on UP rates reported in the literature (32.8%-65.7%).
RESULTS: Among 251,419 beneficiaries, 20,377 pregnancies occurred (8.1%). A total of 52,376 L-IUD users were identified, including 16,398 new insertions (50.5% L-IUD 52 mg; 49.5% L-IUD 19.5 mg). Insertions increased by 80% through 2023, followed by a decline in 2024-2025. The annual pregnancy incidence showed a progressive decrease (3.5%-22%), amounting to a cumulative reduction of 41.8%. The mean cost of prenatal care and delivery was US$ 1.961,34, resulting in total spending of US$ 39.9 million during the period. Considering a UP rate of 65.7%, the associated financial impact was US$ 26.2 million. In prevention scenarios attributing 32.8% or 65.7% reduction in UP to L-IUD use, estimated savings were US$ 7.4 million and US$ 14.8 million, respectively.
CONCLUSIONS: Hormonal IUD use demonstrated a strong association with reduced pregnancy rates and substantial potential for cost savings for the Brazilian Health Insurance Company. Wider adoption of long-acting contraceptive methods represents a cost-effective, high-impact strategy to mitigate UP and their associated financial consequences.

Conference/Value in Health Info

2026-05, ISPOR 2026, Philadelphia, PA, USA

Value in Health, Volume 29, Issue S6

Code

EE281

Topic

Economic Evaluation

Disease

No Additional Disease & Conditions/Specialized Treatment Areas, SDC: Reproductive & Sexual Health

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