Presentation (CTI)

OBJECTIVES: Although oncology affordability programs are increasingly used to improve access to innovative therapies, implementation challenges often limit scalability and long-term sustainability in emerging markets. This study aimed to develop an implementation-oriented framework for prioritizing, operationalizing, and evaluating oncology affordability interventions across diverse healthcare systems.
METHODS: A structured implementation framework was developed using cross-market affordability assessments across 14 markets in Asia-Pacific, Latin America, and the Middle East, including India, Indonesia, Malaysia, Philippines, Thailand, Vietnam, Brazil, Mexico, Argentina, Colombia, Saudi Arabia, Türkiye, United Arab Emirates, and Chile. Affordability barriers were assessed across patient, payer, provider, and healthcare system levels. The framework incorporated standardized implementation tools including affordability diagnostics, patient segmentation approaches, feasibility-versus-impact prioritization matrices, implementation sequencing models, and patient/financial impact estimation tools. Over 70 interventions across the key countries of interest were evaluated according to affordability impact, operational feasibility, scalability, regulatory considerations, and financial sustainability.
RESULTS: Key implementation barriers included fragmented treatment pathways, inconsistent provider engagement, limited diagnostic infrastructure, payer variability, and insufficient real-world data capabilities. Standardized implementation pathways were developed for affordability interventions including patient assistance programs, differential pricing models, co-pay support structures, outcomes-based agreements, and diagnostic access partnerships. Prioritization matrices combining patient impact and implementation feasibility enabled structured classification of interventions into scale, pilot, or deprioritize categories. The framework also incorporated implementation tracking measures including treatment initiation, persistence, patient conversion, and financial impact indicators.
CONCLUSIONS: Operational feasibility is a critical determinant of oncology affordability program success in emerging markets. A structured implementation and prioritization framework may support more consistent translation of affordability interventions into scalable and measurable oncology access programs across heterogeneous healthcare systems.