GUIDANCE ON STAKEHOLDER ENGAGEMENT IN HEALTH EVIDENCE SYNTHESIS IN THAILAND: PRELIMINARY FINDINGS OF THE DEVELOPMENT OF A FRAMEWORK THROUGH NARRATIVE SYNTHESIS OF INTERNATIONAL GUIDANCE...
Author(s)
Phuchit Kontapakdee, PharmD1, Teerapon Dhippayom, PharmD, PhD2, Nathorn Chaiyakunapruk, PharmD, PhD3, Ratree Sawangjit, PhD4, Piyameth Dilokthornsakul, PharmD, PhD5, Panupong Puttarak, PharmD, PhD6, Chanthawat Patikorn, PharmD, PhD7.
1Department of Social and Administrative Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hatyai, Thailand, 2Advancing Collaboration, Translation, and Innovation for Value in Evidence Synthesis (ACTIVES) Hub o, Naresuan University, Muang Phitsanulok, Thailand, 3Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA, 4Faculty of Pharmacy, Mahasarakham, Thailand, 5Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Mueang Chiang Mai, Thailand, 6Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hatyai, Thailand, 7Department of Social and Administrative Pharmacy, Chulalongkorn University, Bangkok, Thailand.
1Department of Social and Administrative Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hatyai, Thailand, 2Advancing Collaboration, Translation, and Innovation for Value in Evidence Synthesis (ACTIVES) Hub o, Naresuan University, Muang Phitsanulok, Thailand, 3Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA, 4Faculty of Pharmacy, Mahasarakham, Thailand, 5Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Mueang Chiang Mai, Thailand, 6Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hatyai, Thailand, 7Department of Social and Administrative Pharmacy, Chulalongkorn University, Bangkok, Thailand.
OBJECTIVES: Stakeholder engagement (SE) in health evidence synthesis is essential for producing evidence that is relevant and implementable for the local context. Thailand lacks a formalized, stepwise SE framework for evidence synthesis processes. This study aimed to develop a comprehensive, evidence-based, stepwise SE framework adapted to the Thai health system context through a targeted literature review of international guidance.
METHODS: PubMed and Google were searched for international guidance on SE in health evidence synthesis. Eligible guidance required: (1) international or national-level endorsement; (2) explicit guidance on SE or patient/public involvement; and (3) relevance to evidence synthesis in healthcare. Principles, phases, domains, and activities described across sources were extracted and synthesized using a narrative framework in the logical chronological sequence of an evidence synthesis cycle. This data extraction and synthesis process was assisted by AI (Claude Sonnet 4.6) and manually verified by humans. Each step was defined by convergent content from three to six source frameworks simultaneously.
RESULTS: Eleven international guidance documents and standards (including WHO, Cochrane, and GRADE frameworks) were included. Six convergent principles were identified across all frameworks: purposeful planning, representativeness and equity, transparency, genuine influence, reflexivity, and reciprocity. Ten sequential steps were identified: (1) Define SE Purpose and Scope; (2) Stakeholder Identification and Mapping; (3) Planning and Resource Allocation; (4) Recruitment and Engagement Methods; (5) Conducting Engagement Activities; (6) Integration into Evidence Synthesis; (7) Feedback and Validation; (8) Reporting and Transparency ; (9) Dissemination and Implementation Support; and (10) Evaluation and Learning.
CONCLUSIONS: This framework provides an operationalized, internationally grounded SE approach bridging international standards and Thai practice. Prospective Delphi validation with Thai experts and empirical evaluation in HTA and guideline development processes is recommended.
METHODS: PubMed and Google were searched for international guidance on SE in health evidence synthesis. Eligible guidance required: (1) international or national-level endorsement; (2) explicit guidance on SE or patient/public involvement; and (3) relevance to evidence synthesis in healthcare. Principles, phases, domains, and activities described across sources were extracted and synthesized using a narrative framework in the logical chronological sequence of an evidence synthesis cycle. This data extraction and synthesis process was assisted by AI (Claude Sonnet 4.6) and manually verified by humans. Each step was defined by convergent content from three to six source frameworks simultaneously.
RESULTS: Eleven international guidance documents and standards (including WHO, Cochrane, and GRADE frameworks) were included. Six convergent principles were identified across all frameworks: purposeful planning, representativeness and equity, transparency, genuine influence, reflexivity, and reciprocity. Ten sequential steps were identified: (1) Define SE Purpose and Scope; (2) Stakeholder Identification and Mapping; (3) Planning and Resource Allocation; (4) Recruitment and Engagement Methods; (5) Conducting Engagement Activities; (6) Integration into Evidence Synthesis; (7) Feedback and Validation; (8) Reporting and Transparency ; (9) Dissemination and Implementation Support; and (10) Evaluation and Learning.
CONCLUSIONS: This framework provides an operationalized, internationally grounded SE approach bridging international standards and Thai practice. Prospective Delphi validation with Thai experts and empirical evaluation in HTA and guideline development processes is recommended.
Conference/Value in Health Info
2026-09, ISPOR Asia Pacific 2026, Bangkok, Thailand
Value in Health, Volume 55, Issue S1
Code
SA8
Topic
Study Approaches
Topic Subcategory
Literature Review & Synthesis
Disease
No Additional Disease & Conditions/Specialized Treatment Areas