VALUING HEALTH STATES: AN EQ-5D-5L VALUE SET FOR UZBEKISTAN
Author(s)
Nilufar Abduvalieva, bachelor1, Bakhrom Mirkasimov, PhD, DSc1, Nilufar Rashitova, PhD1, Bram Roudijk, PhD2, Fanni Rencz, PhD3.
1Research, Westminster International University in Tashkent, Tashkent, Uzbekistan, 2EuroQol Research Foundation, Rotterdam, Netherlands, 3Department of Health Policy, Corvinus University of Budapest, Budapest, Hungary.
1Research, Westminster International University in Tashkent, Tashkent, Uzbekistan, 2EuroQol Research Foundation, Rotterdam, Netherlands, 3Department of Health Policy, Corvinus University of Budapest, Budapest, Hungary.
OBJECTIVES: Developing countries such as Uzbekistan are becoming more interested in health technology assessments and economic evaluations. For the purpose of supporting cost-utility assessments, this study set out to develop an EQ-5D-5L value set based on the preferences of the general population in Uzbekistan.
METHODS: In 2024, respondents from five regions in Uzbekistan were recruited based on two-stage quota sampling strategy to obtain a representative sample for age, gender and region. Employing the EuroQol valuation protocol (EQ-PVT) and standard quality control procedures, trained interviewers assisted participants in completing discrete choice experiment (DCE) and composite time trade-off (cTTO) tasks. Data was analyzed using heteroscedastic tobit, conditional logit and hybrid heteroscedastic tobit models.
RESULTS: Overall, 1007 respondents from Uzbekistan were interviewed. The estimated value for the worst health state (55555) in this study was -0.740. The most important health dimensions were mobility with a utility decrement of 0.530 and pain/discomfort (0.377), which were followed by self-care (0.353), anxiety/depression (0.258), and usual activities (0.222). The highest estimated value for an impaired health state was 0.955 for the 21111.
CONCLUSIONS: The study estimated EQ-5D-5L value set following a standardized protocol for Uzbekistan. To our knowledge, this is the first EQ-5D-5L value set for any Central Asian country. The value set will enable economic evaluations to reflect local preferences, inform health policy decisions and advance health outcomes research in Uzbekistan.
METHODS: In 2024, respondents from five regions in Uzbekistan were recruited based on two-stage quota sampling strategy to obtain a representative sample for age, gender and region. Employing the EuroQol valuation protocol (EQ-PVT) and standard quality control procedures, trained interviewers assisted participants in completing discrete choice experiment (DCE) and composite time trade-off (cTTO) tasks. Data was analyzed using heteroscedastic tobit, conditional logit and hybrid heteroscedastic tobit models.
RESULTS: Overall, 1007 respondents from Uzbekistan were interviewed. The estimated value for the worst health state (55555) in this study was -0.740. The most important health dimensions were mobility with a utility decrement of 0.530 and pain/discomfort (0.377), which were followed by self-care (0.353), anxiety/depression (0.258), and usual activities (0.222). The highest estimated value for an impaired health state was 0.955 for the 21111.
CONCLUSIONS: The study estimated EQ-5D-5L value set following a standardized protocol for Uzbekistan. To our knowledge, this is the first EQ-5D-5L value set for any Central Asian country. The value set will enable economic evaluations to reflect local preferences, inform health policy decisions and advance health outcomes research in Uzbekistan.
Conference/Value in Health Info
2026-09, ISPOR Asia Pacific 2026, Bangkok, Thailand
Value in Health, Volume 55, Issue S1
Code
HTA13
Topic
Health Technology Assessment
Topic Subcategory
Value Frameworks & Dossier Format
Disease
No Additional Disease & Conditions/Specialized Treatment Areas