How to Transform Expert Knowledge Into Evidence for Health Technology Assessment: Optimizing Expert Elicitation Techniques

Speaker(s)

Danielle Riley, MSc, Adelphi Values PROVE™, Macclesfield, UK and Louise Heron, MSc, Adelphi Values PROVE™, Bollington, UK

Presentation Documents

As our industry aims to provide earlier access to novel therapies for patients, there are often instances where there are little to no data available to inform Health Technology Assessment (HTA) decision-making, or there is substantial uncertainty associated with data at the time of submissions. Expert elicitation is an evidence generation technique that is used to elicit evidence using experts’ judgement in the absence of existing data and/or characterise uncertainty to support the assessment of new therapies/technologies. When conducted and applied appropriately, expert elicitation can be leveraged to reduce the impact of uncertainty within HTA submissions, to provide stakeholders with reliable information to inform their decision-making in the absence of patient-level data. For expert elicitation to be leveraged to its full potential in HTA decision-making, it is critical that we ensure suitable efforts are made throughout the elicitation process to adhere to available guidance and increase the confidence of authorities regarding the reliability and credibility of the data produced. This theatre presentation will highlight key considerations and learnings on the conduct of expert elicitation activities, to help provide data at the time of submissions to inform HTA decision-making. We will present recommendations from guidance documents available to help inform appropriate method selection and study design. One such document is the Medical Research Council protocol that has been developed to provide clarity on methods for collecting and using experts’ judgements. This presentation will share our experience in implementing this guidance based on real-world instances and practical examples, ensuring key components such as methods selection, material development, selection of experts, and analyses are appropriate in evidence generation activities. We will illustrate an elicitation exercise through a live practical exercise. A review of criticism found in HTA assessments will be outlined followed by suggestions regarding how they can be overcome.

Sponsor: Adelphi Values

Code

121

Topic

Economic Evaluation