Biosimilar Drugs: Knowledge and Perceptions Among Pharmacists in Algeria

OBJECTIVES: Biosimilar drugs have held a strategic position in the global pharmaceutical market since 2006, as well as in Algeria. The aim of this study was to assess the knowledge and perceptions of pharmacists regarding biosimilars in Algeria.

METHODS: This is a descriptive, observational, cross-sectional study focusing on knowledge, attitudes, and practices. The survey was conducted among pharmacists in Algeria using an anonymous questionnaire distributed online via "Google Forms" during August 2022.

RESULTS: A total of 224 practicing pharmacists in Algeria participated in the survey. The participants had a good understanding of biosimilar drugs and their differences from generics. However, negative perceptions were noted regarding the quality of biosimilars, as well as their interchangeability and the extrapolation of indications. The majority of the surveyed pharmacists were aware of the importance of the "Total of evidence" process steps. Most of them considered that the main perceived drawbacks were the lack of information, immunogenicity, and the extrapolation of indications. On the other hand, the main reported advantages were price reductions and improved access.

CONCLUSIONS: Awareness and training on the safety and efficacy of biosimilars seem necessary to enable their development and safe use. It is also necessary to have a precise regulatory framework concerning these pharmaceutical products.