Trends in Epidemiology and Mortality of Patients With Hyperlipidemia in Germany: A Retrospective Study Using German Claims Data

Speaker(s)

Mevius A1, Müller S2, Dornig S3, Wilke T1
1Institut für Pharmakoökonomie und Arzneimittellogistik (IPAM), Wismar, MV, Germany, 2GIPAM GmbH, Wismar, MV, Germany, 3AOK PLUS, Jena, Germany

Presentation Documents

OBJECTIVES: Despite progress in the early detection and treatment of hyperlipidemia, it remains a common diagnosis in aging populations in Western countries, associated with a substantial cardiovascular event risk. This research aimed to estimate the incidence/prevalence of hyperlipidemia in Germany (GER) and to describe trends in mortality in the last ten years.

METHODS: Utilizing claims data from AOK PLUS (GER sickness fund with 3.5 million insured persons), hyperlipidemia cases were identified by outpatient and inpatient diagnoses (ICD-10-GM: E78). Cumulative incidence in 2012/2022 and point prevalence on January 1st of the following year were assessed and extrapolated (age-/gender-standardized) to the overall GER population. Standardized mortality rates for 2012/2022 were evaluated in cross-sectional hyperlipidemia samples.

RESULTS: Age-/gender-standardized GER hyperlipidemia incidence and prevalence in 2012/2022 were 1.7%/2.0% and 18.7%/20.3%, respectively. Based on a GER population of 83.8 million persons, this translates into 1.65 million incident hyperlipidemia cases in the year 2022 and 17.0 million-prevalent patients on January 1, 2023. Yearly mortality in the extrapolated prevalent GER hyperlipidemia population were 2.4% in 2012 and 3.1% in 2022.

CONCLUSIONS: Hyperlipidemia incidence and prevalence is very high and estimates based on claims data are slightly higher than in other official statistics; every fifth German now suffers from this disease. Even if mortality causes are not exactly known, mortality in hyperlipidemia patients is high and rising. With a continuing aging of the GER population, the health care burden due to this disease is expected to increase further.

Code

EPH111

Topic

Epidemiology & Public Health

Disease

Cardiovascular Disorders (including MI, Stroke, Circulatory), No Additional Disease & Conditions/Specialized Treatment Areas