Health State Utility Values in COVID-19: A Vignette Study in Japan

Speaker(s)

Noto S1, Shimozuma K2, Iwatani T3, Suzukamo Y4, Sakai M5, Moriwaki K6
1Niigata University of Health and Welfare, Niigata, Japan, 2Ritsumeikan University, Kusatsu, 25, Japan, 3St.Marianna University School of Medicine, Kawasaki, Japan, 4Tohoku University Graduate School of Medicine, Sendai, Japan, 5Ritsumeikan University, Kyoto-shi, 26, Japan, 6Ritsumeikan University, Kyoto, 26, Japan

Presentation Documents

OBJECTIVES:

COVID-19 is a respiratory disease caused by the SARS-CoV-2 virus and requires hospitalization and respiratory support in severe cases. Since limited evidences on the health state utility values (HSUV) for COVID-19 patients, we conducted a vignette-based study in Japan, drawing on a previous study in the UK (Goswami H. PharmacoEconomics: 2022).

METHODS:

The health status classification for COVID-19 includes eight categories ranging from mild to severe symptoms, such as general ward, intensive care unit, mechanical ventilation, etc. The vignette in this study was set for each of these eight categories. Respondents were asked to answer questions using the EQ-5D-5L questionnaire. The web-based survey was conducted in July 2023 for 500 healthy general public. The existing Japan EQ-5D-5L value set was then

applied to generate utility values.

RESULTS:

Data from 488 participants were used in the statistical analysis, excluding participants with missing values. 233 males and 255 females were included, and their mean age was 44.7 years. Most participants had received the vaccine (3 or 4 times). EQ values were calculated for each health condition, with scores of 0.387 for Mild/moderate symptoms, 0.248±0.258 for General ward, 0.190±0.187 for Intensive care unit, and 0.115±0.196 for Mechanical ventilation.

CONCLUSIONS:

While the study in the UK showed that the EQ values in general wards were lower than those in intensive care units, this inconsistency was resolved in the current study probably due to our minor modifications on the vignettes. The limitation of this study needs cautious discussions for the way of generating the HSUV using EQ-5D-5L answered by the general public for the given vignettes.

Code

PCR154

Topic

Patient-Centered Research

Topic Subcategory

Health State Utilities, Patient-reported Outcomes & Quality of Life Outcomes

Disease

Infectious Disease (non-vaccine), Respiratory-Related Disorders (Allergy, Asthma, Smoking, Other Respiratory)