Best Research Practice: Does the Practice of Implementation Sciences Have a Place in Industry-Sponsored Research?

PURPOSE: The adoption and integration of new medicines and treatment regimens within healthcare delivery can take more than a decade. This workshop will focus on the use of implementation science (IS) research to bridge this gap between the availability of new therapeutics and use in routine clinical practice. Participants will understand the importance of IS to accelerate the application in industry-sponsored research and improve the use of research evidence and new treatment options in routine care. DESCRIPTION: In this foundational session, workshop attendees will be introduced to IS: 1) specific definitions and concepts; 2) theories, models, and frameworks (TMFs); and 3) applications through case study. Dr. Rodriguez-Leboeuf will chair the session and introduce the core principles of IS, including new guidance for the use of IS principles for regulatory decision-making (European Medicines Agency) (10 min). Dr Gaglio will emphasize the importance of adequate TMFs underpinning research and will describe key TMFs that can help organize and understand context as well as why and how an intervention succeeded or failed (15 min). Ms Zahid will highlight the use and benefits brought by IS to gaps in implementing industry relevant research evidence into routine care using a case study as a supportive example. Factors influencing implementation success and tailoring of effective interventions to different settings will be discussed (15 min). In the practical session, the audience will have the opportunity to analyze a hypothetical case study and engage in critical thinking while applying their newly acquired knowledge for the successful implementation of new treatment options or other research evidence for improved care.