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A Real-World Study to Estimate the Burden of Illness for Patients with Diabetic Peripheral Neuropathic Pain (DPNP)

Speaker(s)

Wang R1, Xuan D2, Hu X3, Xuan J4, Ye X1
1Daiichi Sankyo Inc, Basking Ridge, NJ, USA, 2Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA, 3Shanghai Centennial Scientific Co., Ltd, Shanghai, China, 4Sun Yat-Sen University, Guangzhou, China

OBJECTIVES: Currently, there is no specific characterization of the burden of illness for (DPNP) in most Asian countries nor a dedicated standard of care. The purpose of this research is to understand the burden of illness of DPNP in China from a hospital system perspective.

METHODS: A large EMR database was used to assess the DPNP burden of illness. The database analysis utilized the SuValue® database which covers 182 hospitals across 22 provinces in China and allows the tracing of patients’ electronic medical records for more than 1 year, allowing for longitudinal research. A 12 month pre-and post-index period was used to assess the incremental healthcare resource utilization and cost following the initial diagnosis of DPNP. Differences in utilization and cost of healthcare services were compared between the pre-index and post-index period using the Wilcoxon signed ranks test.

RESULTS: Under the 12-month pre/post-indexing analysis, a total of 7,373 adult patients were identified. 57.24% (N=4,220) of the patients received treatment, and the most common treatment received included analgesics (48.44%), NSAIDS (47.16%), and physical therapies (20.05%). Significant increases were noted in post-index use of all-cause healthcare resource utilization compared to pre-index use for DPNP patients, most notably in the proportion of patients requiring a hospital admission (31.68% vs 17.02%; p <0.001). On average total post-index all-cause healthcare costs were ¥3,376 higher than pre-index (¥7,489 vs ¥4,113; p < 0.05), primarily due to the increase in hospital admissions.

CONCLUSIONS: Relative to the 12-month period beforehand, levels of utilization of healthcare services and costs increased during the 12-month period immediately following the initial diagnosis of DPNP.

Code

RWD137

Topic

Economic Evaluation, Epidemiology & Public Health, Real World Data & Information Systems, Study Approaches

Topic Subcategory

Electronic Medical & Health Records, Health & Insurance Records Systems

Disease

Neurological Disorders