Program

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In-person registration included the full virtual experience, and virtual-only attendees will be able to tune into live in-person sessions and/or watch captured in-person sessions on-demand in addition to having a variety of virtual-only sessions to attend.

Adherence to Breast Cancer Screening Guidelines and Its Association with Survival in Women Treated for Breast Cancer in Colombia: A National Cohort Study Based on Administrative Claims

Speaker(s)

Saldaña Espinel L1, Buitrago G2, Patiño Benavidez A3, Rozo Agudelo N4, Gamboa Ó5, Guevara-Cruz Ó2, Bonilla C6, Caycedo R7, Junca-Burgos E7, Eslava-Schmalbach J8, Sánchez R8
1Universidad Nacional de Colombia, Bogotá, CUN, Colombia, 2Universidad Nacional de Colombia, Hospital Universitario de Colombia, Bogotá, D.C., Colombia, 3Universidad Nacional de Colombia, Bogota, CUN, Colombia, 4Universidad Nacional de Colombia, Bogotá D.C, Colombia, 5Universidad Militar Nueva Granada, Bogotá, Colombia, 6Instituto Nacional de Cancerología, Fundación Colombiana de Cancerología Clínica Vida, Bogota, CUN, Colombia, 7Universidad Nacional de Colombia, Hospital Universitario Nacional de Colombia, Bogotá, D.C., Colombia, 8Universidad Nacional de Colombia, Bogotá, D.C., Colombia

Presentation Documents

Background: Breast cancer (BC) is the most common neoplasm among women in Colombia. Colombian guidelines recommend screening women aged 50 to 69 years with biannual mammography, yet adherence to screening or its impact on mortality at a national level have not been assessed. We aimed to determine adherence to BC screening guidelines and its association with 3-year overall survival in women treated for BC in 2015 in Colombia.

Methods: We conducted a national retrospective cohort study based on administrative claims from the Colombian contributory health regime and the national mortality database. We identified patients eligible for BC screening between 2011-2014 who were first treated for BC in 2015 through a previously validated BC case detection algorithm combining ICE-10 and oncologic procedure codes. Screened patients were those who had at least two mammography codes separated by at least two years. Primary outcome was 3-year survival. We used propensity score methods to balance sociodemographic and clinical covariates and performed a Cox regression with the matched sample to estimate hazard ratios (HR).

Results: 1520 patients were identified. 265 (17.43 %) patients were screened according to guidelines. Mean age was 62.50 (SD 4.66) for screened and 61.83 (SD 4.60) for unscreened patients. Regions with lowest adherence to screening were Pacific (9.06%) and Oriental (9.06%). Mortality rates were 2.64 (CI95% 1.88-3.72) and 4.36 (CI95% 3.85 – 4.95) per 100 person-years, respectively. Adherence to guideline screening recommendations was associated with an improved 3-year survival (HR:0.55 (CI95% 0.37-0.80), and HR:0.58 (CI95% 0.40-0.84) in the unmatched and matched samples, respectively).

Conclusion: BC screening is associated with increased survival in women treated for BC in Colombia. Adherence to BC screening guidelines is low and heterogenous between regions. BC screening adherence can be monitored through administrative claims, and it could become a national indicator of care for women with BC.

Code

RWD133

Topic

Clinical Outcomes, Epidemiology & Public Health, Real World Data & Information Systems, Study Approaches

Topic Subcategory

Clinical Outcomes Assessment, Health & Insurance Records Systems, Public Health

Disease

Oncology