Economic Burden of Patients with Anemia in Selected Diseases

Nov 1, 2005, 00:00
10.1111/j.1524-4733.2005.00058.x
https://www.valueinhealthjournal.com/article/S1098-3015(10)67831-X/fulltext
Title : Economic Burden of Patients with Anemia in Selected Diseases
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(10)67831-X&doi=10.1111/j.1524-4733.2005.00058.x
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Section Title :
Open access? : No
Section Order : 2

Objective

To examine the economic impact of patients with anemia in selected diseases.

Methods

A retrospective cohort design was used to estimate the differences in costs between anemic and nonanemic patients. The analysis used administrative claims data (1999–2001) from a US population to assess direct costs and disability and productivity data (1997–2001) to estimate indirect costs. Adult patients with a diagnosis of rheumatoid arthritis (RA), inflammatory bowel disease (IBD), chronic obstructive pulmonary disease (COPD), chronic kidney disease (CKD), cancer, or congestive heart failure (CHF) were identified. Costs were estimated using a generalized linear model, adjusting for age, sex, comorbidities, and disease severity. The adjustment variables for disease severity were based on ICD-9, HCPCS, or pharmacy codes. These costs were projected to a 1-million-member, similar population.

Results

The percentage of anemia patients varied among conditions (6.9–26.1%); the CKD population had the highest prevalence. CKD anemic patients incurred the greatest average annual direct costs ($78,209), followed by CHF ($72,078) and cancer ($60,447). After adjusting for baseline characteristics including severity, the difference in direct costs between anemic and nonanemic patients decreased for all diseases; CHF patients incurred the greatest adjusted cost difference between anemic and nonanemic ($29,511), followed by CKD ($20,529) and cancer ($18,418). Unmeasured severity and coding bias may account for a portion of the differences in the adjusted cost.

Conclusion

Anemia may substantially increase health-care costs at a level that is economically very relevant, despite the fact that these patients may comprise only one tenth of the overall anemic population.

Categories :
  • Cost-comparison, Effectiveness, Utility, Benefit Analysis
  • Economic Evaluation
  • Retrospective Databases: Electronic Medical and Health Records, Admin Claims
  • Study Approaches
Tags :
  • anemia
  • comorbid conditions
  • economics
  • indirect costs
Regions :
  • North America
ViH Article Tags :