Keeping this fact firmly in focus, the ISPOR Task Force on Good Research Practices in Modeling Studies has produced a welcome and needed addition to the numerous guidelines and checklists that already abound in our field. In a nutshell, models should aim to aid decision makers—not to prove or disprove cost-effectiveness for all time or in all situations. It is generally better to base decisions on imperfect data synthesized in transparent and reasonable models than on no information at all. The good practice principles detailed by this Task Force, under the leadership of its chair Professor Milton Weinstein, provide sound guidance to the producers and users of modeling studies. And,
from the perspective of one who produces economic models directly or indirectly (working with consultants) to inform and influence decision makers—the principles strike just the right balance between sensible practice and scientific rigor, while wisely avoiding the more contentious issues of sponsorship and bias. Although the aim here was clearly to produce general principles, the authors also provide some useful hints and tips along the way, thereby advancing the state of the art.