Lavelle et al. make a timely and methodologically careful contribution by quantifying the enduring health and productivity burdens experienced by parents bereaved by spinal muscular atrophy (SMA) type 1. Their study is notable for linking health-related quality-of-life (HRQoL) decrements and elevated anxiety with work limitations across different time windows since the child’s death, thereby highlighting outcomes commonly missed by cost-effectiveness analyses (CEAs).¹ Building on this strong foundation, we respectfully offer several constructive suggestions to further strengthen the interpretation and translational value of the findings.