Estimating a Preference-Based Index for Mental Health From the Recovering Quality of Life Measure: Valuation of Recovering Quality of Life Utility Index [Editor's Choice]

Feb 1, 2021, 00:00 AM
Section Order : 281
First Page : 281


There are increasing concerns about the appropriateness of generic preference-based measures to capture health benefits in the area of mental health.


The aim of this study is to estimate preference weights for a new measure, Recovering Quality of Life (ReQoL-10), to better capture the benefits of mental healthcare.


Psychometric analyses of a larger sample of mental health service users (n = 4266) using confirmatory factor analyses and item response theory were used to derive a health state classification system and inform the selection of health states for utility assessment. A valuation survey with members of the UK public representative in terms of age, sex, and region was conducted using face-to-face interviewer administered time-trade-off with props. A series of regression models were fitted to the data and the best performing model selected for the scoring algorithm.


The ReQoL-Utility Index (UI) classification system comprises 6 mental health items and 1 physical health item. Sixty-four health states were valued by 305 participants. The preferred model was a random effects model, with significant and consistent coefficients and best model fit. Estimated utilities modeled for all health states ranged from −0.195 (state worse than dead) to 1 (best possible state).


The development of the ReQoL-UI is based on a novel application of item response theory methods for generating the classification system and selecting health states for valuation. Conventional time-trade-off was used to elicit utility values that are modeled to enable the generation of QALYs for use in cost-utility analysis of mental health interventions.
HEOR Topics :
  • Health State Utilities
  • Instrument Development, Validation, & Translation
  • Mental Health
  • Patient-Centered Research
  • Patient-reported Outcomes & Quality of Life Outcomes
  • Specific Diseases & Conditions
  • Stated Preference & Patient Satisfaction
Tags :
  • mental health
  • preference-based measure
  • QALYs
  • ReQoL-10
  • ReQoL-20
Regions :