Machine Learning for Health Services Researchers [Editor's Choice]

Jul 1, 2019, 00:00
10.1016/j.jval.2019.02.012
https://www.valueinhealthjournal.com/article/S1098-3015(19)30146-9/fulltext
Title : Machine Learning for Health Services Researchers [Editor's Choice]
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(19)30146-9&doi=10.1016/j.jval.2019.02.012
First page : 808
Section Title : METHODOLOGY
Open access? : No
Section Order : 808

Background

Machine learning is increasingly used to predict healthcare outcomes, including cost, utilization, and quality.

Objective

We provide a high-level overview of machine learning for healthcare outcomes researchers and decision makers.

Methods

We introduce key concepts for understanding the application of machine learning methods to healthcare outcomes research. We first describe current standards to rigorously learn an estimator, which is an algorithm developed through machine learning to predict a particular outcome. We include steps for data preparation, estimator family selection, parameter learning, regularization, and evaluation. We then compare 3 of the most common machine learning methods: (1) decision tree methods that can be useful for identifying how different subpopulations experience different risks for an outcome; (2) deep learning methods that can identify complex nonlinear patterns or interactions between variables predictive of an outcome; and (3) ensemble methods that can improve predictive performance by combining multiple machine learning methods.

Results

We demonstrate the application of common machine methods to a simulated insurance claims dataset. We specifically include statistical code in R and Python for the development and evaluation of estimators for predicting which patients are at heightened risk for hospitalization from ambulatory care-sensitive conditions.

Conclusions

Outcomes researchers should be aware of key standards for rigorously evaluating an estimator developed through machine learning approaches. Although multiple methods use machine learning concepts, different approaches are best suited for different research problems.

Categories :
  • Artificial Intelligence, Machine Learning, Predictive Analytics
  • Cost-comparison, Effectiveness, Utility, Benefit Analysis
  • Value of Information
Tags :
  • claims data
  • deep learning
  • elastic net
  • gradient boosting machine
  • gradient forest
  • health services research
  • machine learning
  • neural networks
  • random forest
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