Should Linking Replace Regression When Mapping from Profile-Based Measures to Preference-Based Measures?

Mar 1, 2014, 00:00 AM
Section Title : Methodological Articles
Section Order : 13
First Page : 261


Profile instruments are frequently used to assess health-related quality of life and other patient-reported outcomes. However, preference-based measures are required for health-economic cost-utility evaluations.


Although regression-based approaches are commonly used to map from profile measures to preference measures, we show that this results in biased estimates because of regression to the mean.


Linking (scale-aligning) is proposed as an alternative.
HEOR Topics :
  • Methodological & Statistical Research
  • Patient Behavior and Incentives
  • Patient-Centered Research
  • Patient-reported Outcomes & Quality of Life Outcomes
  • Preference Methods
  • PRO & Related Methods
Tags :
  • linking values
  • mapping functions
  • patient-reported outcomes
  • preference-based measures
  • profile instruments
  • scale-aligning
  • test equating
Regions :
  • North America