Quality of Life in the First 6 Weeks Following Laparoscopic and Open Colorectal Surgery

Mar 1, 2013, 00:00
10.1016/j.jval.2012.11.005
https://www.valueinhealthjournal.com/article/S1098-3015(12)04248-9/fulltext
Title : Quality of Life in the First 6 Weeks Following Laparoscopic and Open Colorectal Surgery
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(12)04248-9&doi=10.1016/j.jval.2012.11.005
First page : 367
Section Title : Patient-Reported Outcomes
Open access? : No
Section Order : 15

Objectives

Evidence of how health-related quality of life (HRQOL) changes following laparoscopic and open colorectal surgery in the first 6 weeks of postoperative recovery is needed to inform cost-effectiveness evaluations.

Methods

Pragmatic prospective cohort study design. Consecutive patients requiring elective colorectal surgery were allocated to either laparoscopic or open surgery by administrative staff in a district general hospital in England, 2006-2007. Patients completed two validated, generic measures of HRQOL at baseline (preoperatively) and on multiple occasions in the first 6 weeks postsurgery using diaries (EuroQol five-dimensional [EQ-5D] questionnaire: 16 times; short-form 36 health survey [SF-36]: 4 times; HRQOL was compared between groups at each time point, and overall using repeated-measures analysis.

Results

Of 201 consecutive patients recruited, 32 (15.1%) were unable to complete diaries. Of the remaining 169 patients, 120 (71%) returned completed diaries at 28 days and 105 (62.1%) at 42 days. There was no difference in preoperative HRQOL scores between surgical groups, but the postoperative EQ-5D questionnaire and SF-36 scores were significantly higher in the laparoscopic group (EQ-5D questionnaire P = 0.005, SF-36 P = 0.007). Subgroup analysis showed that patients with a stoma have worse HRQOL than those without. HRQOL did not differ between the laparoscopic and open stoma patients.

Conclusions

This study presents unique prospective data demonstrating that laparoscopic surgery confers HRQOL benefits for patients in the early recovery period following colorectal surgery, compared with open surgery. Consideration of these data in the context of a cost-effectiveness analysis will be reported separately.

Categories :
  • Gastrointestinal Disorders
  • Health State Utilities
  • Patient-Centered Research
  • Specific Diseases & Conditions
Tags :
  • colorectal surgery
  • costs
  • laparoscopy
  • quality of life
Regions :
  • Africa
  • Eastern and Central Europe
ViH Article Tags :