Cost-Effectiveness of a Program to Eliminate Disparities in Pneumococcal Vaccination Rates in Elderly Minority Populations- An Exploratory Analysis

Mar 1, 2013, 00:00
10.1016/j.jval.2012.11.009
https://www.valueinhealthjournal.com/article/S1098-3015(12)04265-9/fulltext
Title : Cost-Effectiveness of a Program to Eliminate Disparities in Pneumococcal Vaccination Rates in Elderly Minority Populations- An Exploratory Analysis
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(12)04265-9&doi=10.1016/j.jval.2012.11.009
First page : 311
Section Title : Economic Evaluation
Open access? : No
Section Order : 9

Objective

Invasive pneumococcal disease is a major cause of preventable morbidity and mortality in the United States, particularly among the elderly (>65 years). There are large racial disparities in pneumococcal vaccination rates in this population. Here, we estimate the cost-effectiveness of a hypothetical national vaccination intervention program designed to eliminate racial disparities in pneumococcal vaccination in the elderly.

Methods

In an exploratory analysis, a Markov decision-analysis model was developed, taking a societal perspective and assuming a 1-year cycle length, 10-year vaccination program duration, and lifetime time horizon. In the base-case analysis, it was conservatively assumed that vaccination program promotion costs were $10 per targeted minority elder per year, regardless of prior vaccination status and resulted in the elderly African American and Hispanic pneumococcal vaccination rate matching the elderly Caucasian vaccination rate (65%) in year 10 of the program.

Results

The incremental cost-effectiveness of the vaccination program relative to no program was $45,161 per quality-adjusted life-year gained in the base-case analysis. In probabilistic sensitivity analyses, the likelihood of the vaccination program being cost-effective at willingness-to-pay thresholds of $50,000 and $100,000 per quality-adjusted life-year gained was 64% and 100%, respectively.

Conclusions

In a conservative analysis biased against the vaccination program, a national vaccination intervention program to ameliorate racial disparities in pneumococcal vaccination would be cost-effective.

Categories :
  • Cost/Cost of Illness/Resource Use Studies
  • Economic Evaluation
  • Respiratory-Related Disorders
  • Specialized Treatment Areas
  • Specific Diseases & Conditions
  • Vaccines
Tags :
  • cost-effectiveness
  • disparities
  • invasive pneumococcal disease
  • vaccination
Regions :
  • North America
ViH Article Tags :