Assessing the Determinants of the Potential for Cost-Effectiveness Over Time- The Empirical Case of COPD

Mar 1, 2013, 00:00
10.1016/j.jval.2012.11.006
https://www.valueinhealthjournal.com/article/S1098-3015(12)04249-0/fulltext
Title : Assessing the Determinants of the Potential for Cost-Effectiveness Over Time- The Empirical Case of COPD
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(12)04249-0&doi=10.1016/j.jval.2012.11.006
First page : 426
Section Title : Health Policy Analysis
Open access? : No
Section Order : 21

Objectives

The objective of this study was to assess the potential for cost-effectiveness of new technologies for chronic obstructive pulmonary disease (COPD) over the period from 2001 to 2010.

Methods

Lung function outcomes and drug prices were observed for a UK COPD population over the period from 2001 to 2010. Cost-effectiveness was assessed at regular intervals on the basis of an established cost-effectiveness model, and the maximum price a technology providing cure could achieve under the current cost-effectiveness rules was estimated.

Results

The results of this study show that although the scope for clinical improvement in COPD was still considerable, during the 10 years studied, the potential for cost-effectiveness at each point in time was dependent on momentary market characteristics, such as the changing price of comparators and improvements in clinical effectiveness. As a result, the analysis demonstrates that the future cost-effectiveness of a technology in development depends on the manner pricing and clinical effectiveness evolve throughout time.

Conclusions

Because any predictions will be short-lived and dependent on a number of uncertain factors, we conclude that producing accurate forecasts on the potential for cost-effectiveness of new therapies earlier during the development process is especially difficult under the current static cost-effectiveness framework.

Categories :
  • Cost-comparison, Effectiveness, Utility, Benefit Analysis
  • Economic Evaluation
  • Respiratory-Related Disorders
  • Specific Diseases & Conditions
Tags :
  • chronic obstructive pulmonary disease
  • cost-effectiveness
  • dynamic efficiency
  • pharmaceutical innovation
  • pharmaceutical policy
  • research and development
Regions :
  • Eastern and Central Europe
ViH Article Tags :