Further Validation of the Uterine Fibroid Symptom and Quality-of-Life Questionnaire

Jan 1, 2012, 00:00
10.1016/j.jval.2011.07.007
https://www.valueinhealthjournal.com/article/S1098-3015(11)01550-6/fulltext
Title : Further Validation of the Uterine Fibroid Symptom and Quality-of-Life Questionnaire
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(11)01550-6&doi=10.1016/j.jval.2011.07.007
First page : 135
Section Title : Patient-Reported Outcomes
Open access? : No
Section Order : 6

Objective

To further examine the reliability, validity and responsiveness of the uterine fibroid symptom and quality-of-life (UFS-QOL) questionnaire among women with and without uterine fibroids.

Methods

A multicenter, non-randomized, prospective study was conducted with women undergoing treatment for uterine fibroids (fibroid treatment group [FTG]) and normal controls (normal control group [NCG]). Women in the FTG were recruited when they were scheduled for treatment; women in the NCG were recruited during their annual exam. Participants completed the UFS-QOL and a short form 36 health survey (SF-36) at enrollment and at 6 and 12 months. Descriptive statistics, Cronbach's alpha, Spearman's correlations, t tests, and general linear models were used to analyze the internal consistency and test–retest reliability, concurrent and discriminant validity, and responsiveness of the UFS-QOL.

Results

There were 89 NCG and 234 FTG women who completed the study. Mean age was 43.1 years for FTG and 40.8 for NCG (P 0.001). The UFS-QOL subscales were significantly correlated in the expected direction and magnitude with each SF-36 subscale in the FTG, indicating acceptable concurrent validity. Cronbach's alphas were 0.73 to 0.97, reflecting adequate internal consistency. Each UFS-QOL subscale was responsive to changes after treatment in the FTG with effect sizes ranging between 1.1 and −2.35. The UFS-QOL remained stable in the NCG during the 1 year follow-up.

Conclusion

The UFS-QOL is a valid and reliable measure to assess symptoms and HRQL in women with uterine fibroids and is highly responsive to treatment-related changes.

Categories :
  • Instrument Development, Validation, & Translation
  • Patient-Centered Research
  • Patient-reported Outcomes & Quality of Life Outcomes
  • Reproductive & Sexual Health
  • Specific Diseases & Conditions
Tags :
  • health-related quality of life
  • patient-reported outcomes
  • symptoms
  • uterine fibroids
Regions :
  • North America
ViH Article Tags :