The Long-Term Outcomes and Costs of Diabetes Mellitus among Renal Transplant Recipients- Tacrolimus versus Cyclosporine

Jun 1, 2011, 00:00
10.1016/j.jval.2010.10.030
https://www.valueinhealthjournal.com/article/S1098-3015(10)00037-9/fulltext
Title : The Long-Term Outcomes and Costs of Diabetes Mellitus among Renal Transplant Recipients- Tacrolimus versus Cyclosporine
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(10)00037-9&doi=10.1016/j.jval.2010.10.030
First page : 443
Section Title : Economic Evaluation
Open access? : No
Section Order : 5

Anti-rejection regimens for renal transplants have changed dramatically during the past 20 years, but there are few long-term studies relating cost, mortality, or graft failure simultaneously to disease-pharmacotherapy couplets. We analyzed US Renal Data System data on a matched-pair cohort of first, single organ kidney transplants from 1998 through 2002 over up to 5 years following transplantation for patients on tacrolimus or low-dose cyclosporine, stratifying by whether the recipient had pre-existing or new onset diabetes. Kaplan-Meier survival curves show mortality and survival differences associated with diabetes, but no additional incremental effects of immune suppression regimen. Significant cost increases are reported for patients receiving tacrolimus above and beyond the extra costs associated with diabetes.

Categories :
  • Cost-comparison, Effectiveness, Utility, Benefit Analysis
  • Diabetes/Endocrine/Metabolic Disorders
  • Economic Evaluation
  • Retrospective Databases: Electronic Medical and Health Records, Admin Claims
  • Specific Diseases & Conditions
  • Study Approaches
  • Urinary/Kidney Disorders
Tags :
  • diabetes
  • long-term costs
  • long-term effects
  • pharmacoeconomics
  • renal transplantation
Regions :
  • North America
ViH Article Tags :