Development of a Conceptual Framework and Calibrated Item Banks to Measure Patient-Reported Dyspnea Severity and Related Functional Limitations

Mar 1, 2011, 00:00
10.1016/j.jval.2010.06.001
https://www.valueinhealthjournal.com/article/S1098-3015(10)00063-X/fulltext
Title : Development of a Conceptual Framework and Calibrated Item Banks to Measure Patient-Reported Dyspnea Severity and Related Functional Limitations
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(10)00063-X&doi=10.1016/j.jval.2010.06.001
First page : 291
Section Title : Outcomes Assessment
Open access? : No
Section Order : 10

Objectives

Chronic obstructive pulmonary disease is a major global health problem. Although several patient-reported outcome (PRO) measures of chronic obstructive pulmonary disease exist, none were developed using patient-driven concept development. We developed an item bank for dyspnea severity and related functional limitations on the basis of a PRO conceptual framework derived from patient input.

Methods

We identified a large pool of existing items based on a conceptual framework and literature review. Using patient and expert review panels and an item refinement/modification process, we developed an item bank aligned with the conceptual framework, which subsequently underwent psychometric testing via an online Internet panel of dyspnea patients (N = 608).

Results

Exploratory factor analysis suggested a dominant first factor accounting for about 78% of the total variance. Confirmatory factor analysis supported a unidimensional model. Item response theory analysis demonstrated good model fit, and differential item functioning analyses indicated that the 33-item scale showed potential for measurement equivalence across sex. A 10-item short form produced comparable scores (r = 0.98) and a computerized adaptive-testing simulation indicated efficient measurement with fewer items (mean 4.65 items).

Conclusions

An efficient patient-reported measure of dyspnea severity and related functional limitations, based on a patient-driven PRO conceptual framework, is now available for further validation and use.

Categories :
  • Instrument Development, Validation, & Translation
  • Methodological & Statistical Research
  • Patient-Centered Research
  • PRO & Related Methods
  • Respiratory-Related Disorders
  • Specific Diseases & Conditions
  • Study Approaches
  • Surveys & Expert Panels
Tags :
  • Computer adaptive testing
  • COPD
  • Dyspnea
  • measurement
  • scale development
Regions :
  • North America
ViH Article Tags :