Interchangeability of the EQ-5D and the SF-6D in Long-Lasting Low Back Pain

Jun 1, 2009, 00:00
10.1111/j.1524-4733.2008.00466.x
https://www.valueinhealthjournal.com/article/S1098-3015(10)60805-4/fulltext
Title : Interchangeability of the EQ-5D and the SF-6D in Long-Lasting Low Back Pain
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(10)60805-4&doi=10.1111/j.1524-4733.2008.00466.x
First page :
Section Title :
Open access? : No
Section Order : 27

Objectives

The objective of this study was to investigate the interchangeability of the EuroQol 5D (EQ-5D) and the Short Form 6D (SF-6D) in individuals with long-lasting low back pain to guide the optimal choice of instrument and to inform decision-makers about any between-measure discrepancy, which require careful interpretation of the results of cost-utility evaluations.

Methods

A cross-sectional study was conducted across 275 individuals who had spinal surgery on indication of chronic low back pain. EQ-5D and SF-6D were mailed to respondents for self-completion. Statistical analysis of between-measure agreement (using English weights) was based on Bland and Altman's limits of agreement and a series of linear regressions.

Results

A moderate mean difference of 0.085 (SD 0.241) was found, but because it masked more severe bidirectional variation, the expected variation between observations of EQ-5D and SF-6D in future studies was estimated at 0.546. The EQ-5D's N3 term alone explained a factor of 0.79 of the variation in between-measure differences, while the explanatory value of adding variables of age, sex, diagnosis, previous surgery, and occupational status was basically zero. A final model including only dummy variables for the N3 term and five identified framing effects explained a factor of 0.86 of the variation in between-measure differences.

Conclusions

Although the EQ-5D and the SF-6D are both psychometrically valid for generic outcome assessment in long-lasting low back pain, it appears that they cannot generally be used interchangeably for measurement of preference values. Sensitivity analysis examining the impact of between-measure discrepancy thus remains a necessary condition for the interpretation of the results of cost-utility evaluations.

Categories :
  • Instrument Development, Validation, & Translation
  • Methodological & Statistical Research
  • Patient-Centered Research
  • PRO & Related Methods
  • Specific Diseases & Conditions
  • Study Approaches
  • Surveys & Expert Panels
  • Systemic Disorders/Conditions
Tags :
  • EQ-5D
  • health-related quality of life
  • low back pain
  • SF-6D
Regions :
  • Western Europe
ViH Article Tags :