Mapping the English and Chinese Versions of the Functional Assessment of Cancer Therapy–General to the EQ-5D Utility Index

Mar 1, 2009, 00:00 AM
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Section Order : 23
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This study aims to develop a function for mapping the English and Chinese versions of the Functional Assessment of Cancer Therapy–General (FACT–G) scores to the EuroQoL Group's EQ-5D utility index and to test whether a single function is sufficient for the two language versions.


A baseline survey of 558 cancer patients in Singapore using the FACT–G and EQ-5D was conducted (308 English and 250 Chinese questionnaires). Regression models were used to predict the EQ-5D utility index values based on the FACT–G scores and thus derive a mapping equation. Data from a follow-up survey of the patients were used to validate the results.


The FACT–G Social/Family scale was not associated with the EQ-5D utility index (P = 0.701). There was no interaction between language version and the predictors (each P > 0.1). An equation that maps the FACT–G Physical, Emotional, and Functional well-being scales to the EQ-5D utility index was derived. In the validation sample, the mean observed utility values was larger than the mapped by only 0.005 (95% confidence interval [CI] −0.006 to 0.016), but the mean absolute difference was 0.083 (95% CI 0.076 to 0.090).


At the group level, but not individual level, the equation developed can accurately map the English and Chinese versions of the FACT–G scores to the EQ-5D utility index.
HEOR Topics :
  • Gastrointestinal Disorders
  • Health State Utilities
  • Patient Behavior and Incentives
  • Patient-Centered Research
  • Patient-reported Outcomes & Quality of Life Outcomes
  • Specialized Treatment Areas
  • Specific Diseases & Conditions
  • Surgery
Tags :
  • cancer
  • EQ-5D
  • FACT–G
  • quality of life
  • utility
Regions :
  • Western Europe