Health Utilities in Patients with HIV/AIDS in Thailand

Mar 1, 2009, 00:00
10.1111/j.1524-4733.2008.00440.x
https://www.valueinhealthjournal.com/article/S1098-3015(10)60718-8/fulltext
Title : Health Utilities in Patients with HIV/AIDS in Thailand
Citation : https://www.valueinhealthjournal.com/action/showCitFormats?pii=S1098-3015(10)60718-8&doi=10.1111/j.1524-4733.2008.00440.x
First page :
Section Title :
Open access? : No
Section Order : 24

Objectives

We measured health utility (HU) in Thai HIV/AIDS patients using visual analog scale (VAS), EuroQOL (EQ-5D), and standard gamble (SG), determine the relationships between these HU measures and health-related quality of life (HRQOL) measures of HIV and patient characteristics, and assess the feasibility of the HU methods.

Methods

A sample of 120 HIV/AIDS patients was identified at Bamrasnaradura Infectious Disease Institute, Thailand, during September to December, 2004. Face-to-face interviews included VAS, SG, and EQ-5D, HRQOL assessment using the Thai abbreviated version of the World Health Organization quality of life (WHOQOL-BREF THAI) and HIV-related symptom instruments, questions about ease of understanding HU approaches and sociodemographic items. Data were analyzed with repeated-measures ANOVA, followed by Dunn–Bonferroni t-test, intraclass coefficients (ICC), Spearman's rank correlation, and multiple linear regressions.

Results

The mean (95% confidence interval) HUs were as follows: VAS, 0.79 (0.76–0.82); EQ-5D, 0.80 (0.77–0.84); and SG, 0.65 (0.60–0.70). A significant difference in HU by method was found (P 0.001). Agreement by ICC was 0.71 for VAS versus EQ-5D, 0.41 for VAS versus SG, and 0.38 for EQ-5D and SG. The regression models showed that WHOQOL-BREF THAI, frequency of HIV symptoms, and patient characteristics could explain approximately 50% of the variation in the VAS and the EQ-5D and 20% in the SG. Among these three HU methods, the SG was the most difficult task.

Conclusion

VAS, EQ-5D and SG yielded different HUs for this sample. VAS and EQ-5D showed stronger construct validity with other health measures than SG. From a feasibility perspective, the SG was the least satisfactory of the three approaches.

Categories :
  • Health State Utilities
  • Patient-Centered Research
  • Reproductive & Sexual Health
  • Specific Diseases & Conditions
  • Study Approaches
  • Surveys & Expert Panels
Tags :
  • EQ-5D
  • health utility
  • HIV/AIDS
  • standard gamble
  • visual analog scale
Regions :
  • Asia Pacific (including Oceania)
ViH Article Tags :