MEDICATION ADHERENCE AND HEALTH CARE DECISIONS

About 25% of patients do not take their medications as prescribed.  If a medicine is prescribed appropriately, 25% non-adherence represents a signicant lost opportunity to improve or maintain a patient’s health status. The papers given below developed by the ISPOR Medication and Persistence Special  Interest Group (MAP SIG) provide insight on the costs of medication non-adherence as well as insights on interventions to improve medication adherence for specific diseases.

COST OF MEDICATION NON-ADHERENCE
Understanding Medication Compliance and Persistence from an Economics Perspective
Citation: Elliott RA, Shinogle JA, Pamela P, et al. Understanding medication compliance and persistence from an economics perspective. Value Health 2008;11:600-10.
Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature
Citation: Salas M, Hughes D, Zuluaga A, et al. Costs of medication nonadherence in patients with diabetes mellitus: a systematic review and critical analysis of the literature. Value Health 2009;12:915-22.
INTERVENTIONS TO IMPROVE MEDICATION ADHERENCE

Systematic Review and Meta-analysis of Interventions to Improve Adherence to Antihypertensives (submitted to Value in Health January 2011)

Diabetes Patient Good Self-Management Practices: A Systemic Review, Critical Appraisal, and Recommendations by the ISPOR Medication Adherence & Persistence Special Interest Group (in development)
Interventions to Improve Dyslipidemia Medication Adherence : A Systematic Review and Critical Analysis by the ISPOR Medication Adherence & Persistence Special Interest Group (in development)
Interventions to Improve Osteoporosis Medication Adherence : A Systematic Review and Critical Analysis by the ISPOR Medication Adherence & Persistence Special Interest Group  (in development)
Interventions to Improve Respiratory Infection Medication Adherence: A Systematic Review and Critical Analysis by the ISPOR Medication Adherence & Persistence Special Interest Group (in development)