IN-HOSPITAL ECONOMIC BURDEN OF ANASTOMOTIC LEAKAGE AFTER COLORECTAL ANASTOMOSIS SURGERY- A REAL-WORLD COST ANALYSIS
Author(s)
Capolupo GT1, Galvain T2, Paragò V3, Tong C4, Mascianà G1, Orsini A1, Di Berardino S5, Caricato M1
1Policlinico Universitario Campus Bio-Medico of Rome, Rome, Italy, 2Johnson & Johnson Medical SAS, Paris, France, 3Johnson & Johnson Medical SpA, Pratica di Mare (Rome), Italy, 4Johnson & Johnson Medical, Somerville, NJ, USA, 5Policlinico Universitario Campus Bio-Medico of Rome, Avezzano, AQ, Italy
OBJECTIVES: Anastomotic Leakage (AL) is a serious complication that may follow colorectal resection, increasing overall costs. The aim of this study was to assess the additional inpatient economic burden of AL at one Italian hospital. METHODS: RESULTS: Mean (SD) age in the cohort was 66.7 (13.2) years and 51.8% of patients were male. 79.5% of patients had malignant disease and 58.9% had an American Society of Anesthesiologists (ASA) score of 2/6. More patients had laparoscopic surgery (72.6%) compared to open, in 23% of cases derivative stoma was made during the primary operation. 39 patients (12.3%) developed AL during hospital stay. When compared to patients without AL, more AL patients were male (71.8% vs 51.8%), more had cancer (92.3% vs 77.7%) and more had a derivative stoma (20.5% vs. 9.9%). Age, surgery approach, are similar in two groups. In the bivariate analysis, patients with AL had significantly higher total inpatient costs (€14,781.8 vs €7,110.8, p<0.001), higher LOS (20.1 vs 10.3 days, p<0.001) and ICU admissions (38.5% vs 9.0%, p<0.001) relative to patients without AL. CONCLUSIONS: AL increases the inpatient costs 2 times in this Italian hospital. Reducing AL may improve quality of care and substantially reduce hospital costs while increasing the efficiency of resource utilization.
Conference/Value in Health Info
2018-11, ISPOR Europe 2018, Barcelona, Spain
Value in Health, Vol. 21, S3 (October 2018)
Code
PMU46
Topic
Economic Evaluation
Topic Subcategory
Cost/Cost of Illness/Resource Use Studies
Disease
Multiple Diseases