FOOD NOISE DURING GLUCAGON-LIKE PEPTIDE-1 (GLP-1) MAINTENANCE: A SOCIAL MEDIA LISTENING ANALYSIS OF UK PATIENT COMMUNITIES

Author(s)

Sara Boretti, MSc1, Pippa Brown, MA1, Marjorie Jacqueline Leclerc, MA, MD2, Lysel Brignoli, MS2, Vicky Britton, MA1.
1Oracle Life Sciences, London, United Kingdom, 2Oracle Life Sciences, Paris, France.
OBJECTIVES: As GLP-1 users transition to weight-loss maintenance, some report the return of food noise, a persistent preoccupation with food. This study aims to characterise patient-reported experiences of food noise and the strategies used to manage it during this phase.
METHODS: English-language posts were collected from UK GLP-1-focused subreddits between 1 May 2025 and 31 May 2026 using third-party social listening tool Brandwatch. Posts were required to reference both GLP-1 maintenance and food noise, refining the dataset to patients discussing food noise in the context of weight-loss maintenance. The final dataset was analysed using keyword frequency analysis and grounded theory.
RESULTS: Across 672 posts, food noise re-emergence during maintenance was associated with anxiety and fear (n=122), prompted redefinitions of success and failure relative to maintenance goals (n=61), and was characterised by its frequency and persistence (n=176) and intensity (n=152). GLP-1 users described dose adjustment strategies to minimise food noise during maintenance, including gradual dose reduction (n=242), tapering (n=56), and extending the interval between injections (n=37). A smaller subset reported sustained low-dose use as a longer-term management strategy (n=16). Peer advice and support around maintenance and food noise re-emergence was also actively sought online (n=102).
CONCLUSIONS: Social media discussions suggest that challenges with GLP-1 maintenance extend beyond weight regain to psychological burden of food noise. With limited clinical guidance available, patients describe relying on trial-and-error dosing adjustments to manage food noise while avoiding weight regain. These findings highlight a lack of awareness of food noise's psychological impact and an unmet need for evidence-based support to help patients navigate this phase of treatment.

Conference/Value in Health Info

2026-11, ISPOR Europe 2026, Vienna, Austria

Value in Health, Volume 29, Issue 12S

Code

PCR224

Topic

Patient-Centered Research, Study Approaches

Topic Subcategory

Patient-reported Outcomes & Quality of Life Outcomes

Disease

Diabetes/Endocrine/Metabolic Disorders (including obesity)

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