Study Design in Pharmacoeconomics
The growing access, at least in the United States (and to a lesser extent, Canada) to medical and pharmacy claims databases, has widened considerably the scope for pharmacoeconomic evaluations. At the same time, it has opened up another area of analysis to which those working in the field should become familiar: econometrics and the application of econometric estimating techniques to hypothesis testing with retrospective data. To the traditional experimental and quasi-experimental study designs, we now have to add the subject of non-experimental designs. Even so, the issue of experimental design for prospective randomized studies is of continuing importance in pharmacoeconomics, particularly as these are not only becoming more naturalistic and long-term in nature, but also because experimental designs are being used increasingly to evaluate disease management intervention models. Three core units are presented: Study Design in Pharmacoeconomic Analysis, Experimental Designs, Non-Experimental Designs, and Public and Private Data Sets in the US: Their Role in Pharmacoeconomic Analysis.